Innovative approach to preparing radial artery cocktails in response to manufacturer shortages of nitroglycerin and verapamil

Rupal K. Parbhoo, Karen Wetz, Marva Tschampel, Vincent Pompili, Elena Schenko, Lou Mavko, Danielle Blais

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Transradial access has gained popularity over transfemoral access for cardiac catheterization, because of the decreased risk of bleeding, time to ambulation, and length of stay leading to improved patient satisfaction. One disadvantage of the radial artery approach is vasospasm, which can be prevented with the administration of verapamil and nitroglycerin in a pre- and postradial cocktail. Unfortunately, there have been manufacturer shortages for both of these medications. Methods: The utilization of radial artery cocktails and other nitroglycerin compounding practices were evaluated in response to cost containment and waste reduction initiatives and to medication shortages. Results: A modified process for supplying verapamil and nitroglycerin for the transradial approach via separate syringes enabled physicians to have quick access to the medications and to customize the cocktail based on the patient's needs. This process also decreased costs and minimized wastage. The change in practice decreased waste from 44% for preradial cocktail syringes and 66% for postradial cocktail syringes to 8.7%. Discussion: This process for supplying the medications necessary to perform a radial artery catheterization and intracoronary nitroglycerin has allowed for conservation of commercial product supply.

Original languageEnglish (US)
Pages (from-to)628-633
Number of pages6
JournalHospital Pharmacy
Volume49
Issue number7
DOIs
StatePublished - Jan 1 2014

Fingerprint

Radial Artery
Nitroglycerin
Verapamil
Syringes
Bleeding Time
Cost Control
Cardiac Catheterization
Patient Satisfaction
Catheterization
Walking
Costs
Length of Stay
Conservation
Physicians
Costs and Cost Analysis

Keywords

  • cardiac catheterization
  • drug shortage
  • nitroglycerin
  • radial artery spasm
  • stability
  • transradial
  • verapamil

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Pharmacy

Cite this

Parbhoo, R. K., Wetz, K., Tschampel, M., Pompili, V., Schenko, E., Mavko, L., & Blais, D. (2014). Innovative approach to preparing radial artery cocktails in response to manufacturer shortages of nitroglycerin and verapamil. Hospital Pharmacy, 49(7), 628-633. https://doi.org/10.1310/hpj4907-628

Innovative approach to preparing radial artery cocktails in response to manufacturer shortages of nitroglycerin and verapamil. / Parbhoo, Rupal K.; Wetz, Karen; Tschampel, Marva; Pompili, Vincent; Schenko, Elena; Mavko, Lou; Blais, Danielle.

In: Hospital Pharmacy, Vol. 49, No. 7, 01.01.2014, p. 628-633.

Research output: Contribution to journalArticle

Parbhoo, RK, Wetz, K, Tschampel, M, Pompili, V, Schenko, E, Mavko, L & Blais, D 2014, 'Innovative approach to preparing radial artery cocktails in response to manufacturer shortages of nitroglycerin and verapamil', Hospital Pharmacy, vol. 49, no. 7, pp. 628-633. https://doi.org/10.1310/hpj4907-628
Parbhoo, Rupal K. ; Wetz, Karen ; Tschampel, Marva ; Pompili, Vincent ; Schenko, Elena ; Mavko, Lou ; Blais, Danielle. / Innovative approach to preparing radial artery cocktails in response to manufacturer shortages of nitroglycerin and verapamil. In: Hospital Pharmacy. 2014 ; Vol. 49, No. 7. pp. 628-633.
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