### Abstract

Using the mathematical bases of information theory, we present a model to describe the transfer of information between sites of an allosteric enzyme. This model makes testable predictions about the behavior of the enzyme under various definable conditions. The transfer of information from regulatory to catalytic sites is modeled in terms of a communication system. The model is discussed in terms of the known characteristics of beef heart mitochondrial adenosine triphosphate (ATP)ase, but the general applicability of the model is proposed.

Original language | English (US) |
---|---|

Pages (from-to) | 187-206 |

Number of pages | 20 |

Journal | Applied physics communications |

Volume | 4 |

Issue number | 2-3 |

State | Published - Dec 1 1984 |

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### ASJC Scopus subject areas

- Engineering(all)

### Cite this

*Applied physics communications*,

*4*(2-3), 187-206.

**INFORMATION THEORETIC MODEL FOR ALLOSTERIC ENZYMES : THEORY.** / Daggett, Stephen G.; Schuster, Sheldon M.; Sayood, Khalid.

Research output: Contribution to journal › Article

*Applied physics communications*, vol. 4, no. 2-3, pp. 187-206.

}

TY - JOUR

T1 - INFORMATION THEORETIC MODEL FOR ALLOSTERIC ENZYMES

T2 - THEORY.

AU - Daggett, Stephen G.

AU - Schuster, Sheldon M.

AU - Sayood, Khalid

PY - 1984/12/1

Y1 - 1984/12/1

N2 - Using the mathematical bases of information theory, we present a model to describe the transfer of information between sites of an allosteric enzyme. This model makes testable predictions about the behavior of the enzyme under various definable conditions. The transfer of information from regulatory to catalytic sites is modeled in terms of a communication system. The model is discussed in terms of the known characteristics of beef heart mitochondrial adenosine triphosphate (ATP)ase, but the general applicability of the model is proposed.

AB - Using the mathematical bases of information theory, we present a model to describe the transfer of information between sites of an allosteric enzyme. This model makes testable predictions about the behavior of the enzyme under various definable conditions. The transfer of information from regulatory to catalytic sites is modeled in terms of a communication system. The model is discussed in terms of the known characteristics of beef heart mitochondrial adenosine triphosphate (ATP)ase, but the general applicability of the model is proposed.

UR - http://www.scopus.com/inward/record.url?scp=0021578651&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021578651&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0021578651

VL - 4

SP - 187

EP - 206

JO - Applied physics communications

JF - Applied physics communications

SN - 0277-9374

IS - 2-3

ER -