Influence of menopausal status on sleep and hot flashes throughout breast cancer adjuvant chemotherapy

Ann Malone Berger, Heather A. Treat Marunda, Sangeeta Agrawal

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objectives: To examine the patterns and differences among sleep and hot flashes based on menopausal status (pre, peri, or post) in breast cancer adjuvant chemotherapy patients before, during, and after treatment. Design: Secondary analysis from a randomized clinical trial. Setting: Outpatient clinics and participants' homes. Patients/Participants: Two hundred nineteen (219) women; mean age of 52 years (29-79); postoperative, Stages I to IIIA breast cancer. Methods: Participants were randomized to a behavioral sleep intervention or a healthy eating control group. Variables measured were menopausal status (self-report), subjective sleep (Pittsburgh Sleep Quality Index), objective sleep (actigraphy), perceived interruption of sleep by hot flashes (diary), and demographic/medical characteristics. Data reported were collected 48 hours before initial chemotherapy, at treatment 4, and 30 days after the last treatment. Analysis included descriptives and repeated measures mixed model analysis of variance. Results: Objective sleep and the perceived interruption of sleep by hot flashes changed significantly over time. Sleep and hot flashes differed over time by menopausal status. Only hot flashes were significantly different by study group and by menopausal status over time. Conclusion: Women's menopausal status when starting chemotherapy was associated with differing patterns of sleep and hot flashes over time.

Original languageEnglish (US)
Pages (from-to)353-366
Number of pages14
JournalJOGNN - Journal of Obstetric, Gynecologic, and Neonatal Nursing
Volume38
Issue number3
DOIs
StatePublished - Jan 1 2009

Fingerprint

Hot Flashes
Adjuvant Chemotherapy
Sleep
Breast Neoplasms
Actigraphy
Drug Therapy
Women's Rights
Ambulatory Care Facilities
Self Report
Analysis of Variance
Therapeutics
Randomized Controlled Trials
Demography

Keywords

  • Actigraph
  • Adjuvant chemotherapy
  • Breast cancer
  • Hot flashes
  • Insomnia
  • Menopausal status
  • Sleep

ASJC Scopus subject areas

  • Pediatrics
  • Critical Care
  • Maternity and Midwifery

Cite this

Influence of menopausal status on sleep and hot flashes throughout breast cancer adjuvant chemotherapy. / Berger, Ann Malone; Treat Marunda, Heather A.; Agrawal, Sangeeta.

In: JOGNN - Journal of Obstetric, Gynecologic, and Neonatal Nursing, Vol. 38, No. 3, 01.01.2009, p. 353-366.

Research output: Contribution to journalArticle

@article{a6b798a800984d69a74638a111bd577e,
title = "Influence of menopausal status on sleep and hot flashes throughout breast cancer adjuvant chemotherapy",
abstract = "Objectives: To examine the patterns and differences among sleep and hot flashes based on menopausal status (pre, peri, or post) in breast cancer adjuvant chemotherapy patients before, during, and after treatment. Design: Secondary analysis from a randomized clinical trial. Setting: Outpatient clinics and participants' homes. Patients/Participants: Two hundred nineteen (219) women; mean age of 52 years (29-79); postoperative, Stages I to IIIA breast cancer. Methods: Participants were randomized to a behavioral sleep intervention or a healthy eating control group. Variables measured were menopausal status (self-report), subjective sleep (Pittsburgh Sleep Quality Index), objective sleep (actigraphy), perceived interruption of sleep by hot flashes (diary), and demographic/medical characteristics. Data reported were collected 48 hours before initial chemotherapy, at treatment 4, and 30 days after the last treatment. Analysis included descriptives and repeated measures mixed model analysis of variance. Results: Objective sleep and the perceived interruption of sleep by hot flashes changed significantly over time. Sleep and hot flashes differed over time by menopausal status. Only hot flashes were significantly different by study group and by menopausal status over time. Conclusion: Women's menopausal status when starting chemotherapy was associated with differing patterns of sleep and hot flashes over time.",
keywords = "Actigraph, Adjuvant chemotherapy, Breast cancer, Hot flashes, Insomnia, Menopausal status, Sleep",
author = "Berger, {Ann Malone} and {Treat Marunda}, {Heather A.} and Sangeeta Agrawal",
year = "2009",
month = "1",
day = "1",
doi = "10.1111/j.1552-6909.2009.01030.x",
language = "English (US)",
volume = "38",
pages = "353--366",
journal = "JOGNN - Journal of Obstetric, Gynecologic, and Neonatal Nursing",
issn = "0884-2175",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Influence of menopausal status on sleep and hot flashes throughout breast cancer adjuvant chemotherapy

AU - Berger, Ann Malone

AU - Treat Marunda, Heather A.

AU - Agrawal, Sangeeta

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Objectives: To examine the patterns and differences among sleep and hot flashes based on menopausal status (pre, peri, or post) in breast cancer adjuvant chemotherapy patients before, during, and after treatment. Design: Secondary analysis from a randomized clinical trial. Setting: Outpatient clinics and participants' homes. Patients/Participants: Two hundred nineteen (219) women; mean age of 52 years (29-79); postoperative, Stages I to IIIA breast cancer. Methods: Participants were randomized to a behavioral sleep intervention or a healthy eating control group. Variables measured were menopausal status (self-report), subjective sleep (Pittsburgh Sleep Quality Index), objective sleep (actigraphy), perceived interruption of sleep by hot flashes (diary), and demographic/medical characteristics. Data reported were collected 48 hours before initial chemotherapy, at treatment 4, and 30 days after the last treatment. Analysis included descriptives and repeated measures mixed model analysis of variance. Results: Objective sleep and the perceived interruption of sleep by hot flashes changed significantly over time. Sleep and hot flashes differed over time by menopausal status. Only hot flashes were significantly different by study group and by menopausal status over time. Conclusion: Women's menopausal status when starting chemotherapy was associated with differing patterns of sleep and hot flashes over time.

AB - Objectives: To examine the patterns and differences among sleep and hot flashes based on menopausal status (pre, peri, or post) in breast cancer adjuvant chemotherapy patients before, during, and after treatment. Design: Secondary analysis from a randomized clinical trial. Setting: Outpatient clinics and participants' homes. Patients/Participants: Two hundred nineteen (219) women; mean age of 52 years (29-79); postoperative, Stages I to IIIA breast cancer. Methods: Participants were randomized to a behavioral sleep intervention or a healthy eating control group. Variables measured were menopausal status (self-report), subjective sleep (Pittsburgh Sleep Quality Index), objective sleep (actigraphy), perceived interruption of sleep by hot flashes (diary), and demographic/medical characteristics. Data reported were collected 48 hours before initial chemotherapy, at treatment 4, and 30 days after the last treatment. Analysis included descriptives and repeated measures mixed model analysis of variance. Results: Objective sleep and the perceived interruption of sleep by hot flashes changed significantly over time. Sleep and hot flashes differed over time by menopausal status. Only hot flashes were significantly different by study group and by menopausal status over time. Conclusion: Women's menopausal status when starting chemotherapy was associated with differing patterns of sleep and hot flashes over time.

KW - Actigraph

KW - Adjuvant chemotherapy

KW - Breast cancer

KW - Hot flashes

KW - Insomnia

KW - Menopausal status

KW - Sleep

UR - http://www.scopus.com/inward/record.url?scp=65949103422&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=65949103422&partnerID=8YFLogxK

U2 - 10.1111/j.1552-6909.2009.01030.x

DO - 10.1111/j.1552-6909.2009.01030.x

M3 - Article

C2 - 19538625

AN - SCOPUS:65949103422

VL - 38

SP - 353

EP - 366

JO - JOGNN - Journal of Obstetric, Gynecologic, and Neonatal Nursing

JF - JOGNN - Journal of Obstetric, Gynecologic, and Neonatal Nursing

SN - 0884-2175

IS - 3

ER -