Inflammatory thoughts about glioma gene therapy

Tammy Kielian, William F. Hickey

Research output: Contribution to journalShort survey

25 Scopus citations

Abstract

Gene therapy for treatment of glioma often involves delivery of herpes simplex virus-1 thymidine kinase gene. A new study shows that this approach can induce chronic inflammation, and raises important questions about current adenoviral-based clinical trials (pages 1256-1263).

Original languageEnglish (US)
Pages (from-to)1237-1238
Number of pages2
JournalNature Medicine
Volume5
Issue number11
DOIs
StatePublished - Nov 1 1999

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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