Infection and atherosclerosis: Mechanisms involving Chlamydia pneumoniae in cardiovascular disease

Gerald I. Byrne, Scot P. Ouellette, Robert J. Belland

Research output: Contribution to journalArticle

Abstract

The intracellular bacterium Chlamydia pneumoniae is present in atherosclerotic plaques and may contribute to progression and vulnerability of lesions. Results from animal models support a causal role for C. pneumoniae in atherosclerosis and virulence attributes ascribed to this organism are consistent with this view. Results from recent antibiotic treatment trials have not proven effective, but additional work is needed to define reasons for these failures.

Original languageEnglish (US)
Pages (from-to)426-429
Number of pages4
JournalInternational Congress Series
Volume1262
Issue numberC
DOIs
StatePublished - May 1 2004

    Fingerprint

Keywords

  • Atherosclerosis
  • Chlamydia pneumoniae
  • Chronic infection
  • GroEL
  • Pathogenesis

ASJC Scopus subject areas

  • Medicine(all)

Cite this