Incidence, Duration, and Prevalence of Escherichia coli O157:H7 Fecal Shedding by Feedlot Cattle during the Finishing Period

M. L. Khaitsa, D. R. Smith, J. A. Stoner, A. M. Parkhurst, S. Hinkley, T. J. Klopfenstein, R. A. Moxley

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

The objective was to describe variability in prevalence, incidence, and duration of fecal shedding of naturally occurring E. coli O157:H7 by a group of feedlot cattle over time. One hundred steers, randomly assigned to 10 pens, were fed a high-concentrate finishing diet for 136 days (19 weeks). Rectal feces from each animal were tested for E. coli O157:H7 every week for 19 weeks. E. coli O157:H7 was recovered from each animal that completed the study and was detected from at least one animal every week. Average pen prevalence of cattle shedding E. coli O157:H7 varied significantly over time (P < 0.0001) and across pens (P < 0.0001), ranging from 1 to 80%. Pairwise comparisons of mean pen prevalence of E. coli O157:H7 between weeks and estimation of the predicted probability of an incident case of E. coli O157:H7 over time allowed the definition of three distinct phases - namely, the preepidemic, epidemic, and postepidemic periods. Average pen prevalence varied significantly over time (P < 0.01) and across pens (P < 0.001) for all time periods. The odds of an incident case were significantly greater during epidemic and postepidemic periods relative to the preepidemic period (P = 0.0002 and P = 0.03, respectively). Duration of infection was significantly longer for first or second infections that began during epidemic or postepidemic periods relative to the preepidemic period (P < 0.001). Both incidence and duration of shedding peaked during the epidemic period. Pen-level prevalence of cattle shedding E. coli O157:H7 was affected by both incidence and duration of shedding and could be explained by time- or pen-dependent risk factors, or both.

Original languageEnglish (US)
Pages (from-to)1972-1977
Number of pages6
JournalJournal of food protection
Volume66
Issue number11
DOIs
StatePublished - Nov 2003

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Escherichia coli O157
feedlots
finishing
incidence
duration
cattle
Incidence
animals
Penicillin G
Infection
Feces
infection
risk factors
concentrates
feces
Diet
diet

ASJC Scopus subject areas

  • Food Science
  • Microbiology

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Incidence, Duration, and Prevalence of Escherichia coli O157:H7 Fecal Shedding by Feedlot Cattle during the Finishing Period. / Khaitsa, M. L.; Smith, D. R.; Stoner, J. A.; Parkhurst, A. M.; Hinkley, S.; Klopfenstein, T. J.; Moxley, R. A.

In: Journal of food protection, Vol. 66, No. 11, 11.2003, p. 1972-1977.

Research output: Contribution to journalArticle

Khaitsa, M. L. ; Smith, D. R. ; Stoner, J. A. ; Parkhurst, A. M. ; Hinkley, S. ; Klopfenstein, T. J. ; Moxley, R. A. / Incidence, Duration, and Prevalence of Escherichia coli O157:H7 Fecal Shedding by Feedlot Cattle during the Finishing Period. In: Journal of food protection. 2003 ; Vol. 66, No. 11. pp. 1972-1977.
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