Inactivation of transforming DNA by a transient product of the interaction of Cu2+ and hydroquinone

George R. Dubes, Anthony R. Sambol, Moslih I. Al-Moslin, Gary L. Bradshaw

Research output: Contribution to journalArticle

2 Scopus citations


Cu2+ and hydroquinone interact to produce a transient inactivator(s) of the transforming activity of isolated double-stranded DNA from Bacillus, subtilis. The inactivation is single-hit. Though highly sensitive to the inactivator(s), the transforming activity of the DNA is still much less sensitive than the transfectivity of single-stranded RNA isolated from poliovirions, as determined by direct comparison using a mixture of the bacterial DNA and viral RNA.

Original languageEnglish (US)
Pages (from-to)888-894
Number of pages7
JournalBiochemical and Biophysical Research Communications
Issue number3
Publication statusPublished - Dec 15 1982


ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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