Absorption of folates, thiamin, vitamin B 6, pantothenate and riboflavin from a natural food source - yeast - and their respective synthetic forms was studied in 36 patients with liver disease due to alcoholism, and 12 healthy, nonalcoholic subjects. All alcoholics absorbed riboflavin and pantothenate but had a significantly lowered absorption of thiamin and vitamin B 6 from yeast. Alcoholics absorbed synthetic vitamin B 6 but not thiamin. Ingested folylpolyglutamates (the predominant folates in yeast) could not serve as a source of folate for the alcoholics, but synthetic folylmonoglutamate served. It was suggested that the folate, vitamin B 6 and thiamin deficits so common in alcoholic liver disease ensue from inability to absorb these specific vitamins from foods.
|Original language||English (US)|
|Number of pages||4|
|Journal||American Journal of Clinical Nutrition|
|State||Published - Dec 1 1975|
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics