Immunodetection of keratin proteins in oral epithelial neoplasms.

Nagamani Narayana, D. Gadewar

Research output: Contribution to journalArticle

Abstract

Immunoperoxidase technique was used as an adjunct to routine Haematoxylin and Eosin Staining to assess the pattern of distribution and intensity of Keratin in Oral epithelial neoplasms. The specimens of papillomas, verrucous carcinomas and squamous cell carcinomas were studied. The broadly reactive polyclonal antikeratin antibodies were reacted with formalin fixed paraffin embedded sections. The staining of keratin proteins was found to be dependent upon the degree of differentiation of the tumour. It was observed that the pattern of keratin distribution was regular in papillomas while it was disturbed in verrucous carcinomas and squamous cell carcinomas.

Original languageEnglish (US)
Pages (from-to)68-75
Number of pages8
JournalIndian journal of dental research : official publication of Indian Society for Dental Research
Volume3
Issue number3
StatePublished - Jul 1 1992

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Glandular and Epithelial Neoplasms
Mouth Neoplasms
Keratins
Verrucous Carcinoma
Papilloma
Squamous Cell Carcinoma
Staining and Labeling
Proteins
Hematoxylin
Eosine Yellowish-(YS)
Immunoenzyme Techniques
Paraffin
Formaldehyde
Antibodies
Neoplasms

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

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