Image background removal in comprehensive two-dimensional gas chromatography

Stephen E. Reichenbach, Mingtian Ni, Dongmin Zhang, Edward B. Ledford

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

This paper describes a new technique for removing the background level from digital images produced in comprehensive two-dimensional gas chromatography (GC×GC). Background removal is an important first step in the larger problem of quantitative analysis. The approach estimates the background level across the chromatographic image based on structural and statistical properties of GC×GC data. Then, the background level is subtracted from the image, producing a chromatogram in which the peaks rise above a near-zero mean background. After the background level is removed, further analysis is required to determine the quantitative relationship between the peaks and chemicals in the sample. The algorithm is demonstrated experimentally to be effective at determining and removing the background level from GC×GC images. The algorithm has several parametric controls and is incorporated into an interactive program with graphical interface for rapid and accurate detection of GC×GC peaks.

Original languageEnglish (US)
Pages (from-to)47-56
Number of pages10
JournalJournal of Chromatography A
Volume985
Issue number1-2
DOIs
StatePublished - Jan 24 2003

Fingerprint

Gas chromatography
Gas Chromatography
Chemical analysis

Keywords

  • Gas chromatography, comprehensive two-dimensional
  • Image background removal

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

Cite this

Image background removal in comprehensive two-dimensional gas chromatography. / Reichenbach, Stephen E.; Ni, Mingtian; Zhang, Dongmin; Ledford, Edward B.

In: Journal of Chromatography A, Vol. 985, No. 1-2, 24.01.2003, p. 47-56.

Research output: Contribution to journalArticle

Reichenbach, Stephen E. ; Ni, Mingtian ; Zhang, Dongmin ; Ledford, Edward B. / Image background removal in comprehensive two-dimensional gas chromatography. In: Journal of Chromatography A. 2003 ; Vol. 985, No. 1-2. pp. 47-56.
@article{ea039658109548d3b35cb794140a3005,
title = "Image background removal in comprehensive two-dimensional gas chromatography",
abstract = "This paper describes a new technique for removing the background level from digital images produced in comprehensive two-dimensional gas chromatography (GC×GC). Background removal is an important first step in the larger problem of quantitative analysis. The approach estimates the background level across the chromatographic image based on structural and statistical properties of GC×GC data. Then, the background level is subtracted from the image, producing a chromatogram in which the peaks rise above a near-zero mean background. After the background level is removed, further analysis is required to determine the quantitative relationship between the peaks and chemicals in the sample. The algorithm is demonstrated experimentally to be effective at determining and removing the background level from GC×GC images. The algorithm has several parametric controls and is incorporated into an interactive program with graphical interface for rapid and accurate detection of GC×GC peaks.",
keywords = "Gas chromatography, comprehensive two-dimensional, Image background removal",
author = "Reichenbach, {Stephen E.} and Mingtian Ni and Dongmin Zhang and Ledford, {Edward B.}",
year = "2003",
month = "1",
day = "24",
doi = "10.1016/S0021-9673(02)01498-X",
language = "English (US)",
volume = "985",
pages = "47--56",
journal = "Journal of Chromatography A",
issn = "0021-9673",
number = "1-2",

}

TY - JOUR

T1 - Image background removal in comprehensive two-dimensional gas chromatography

AU - Reichenbach, Stephen E.

AU - Ni, Mingtian

AU - Zhang, Dongmin

AU - Ledford, Edward B.

PY - 2003/1/24

Y1 - 2003/1/24

N2 - This paper describes a new technique for removing the background level from digital images produced in comprehensive two-dimensional gas chromatography (GC×GC). Background removal is an important first step in the larger problem of quantitative analysis. The approach estimates the background level across the chromatographic image based on structural and statistical properties of GC×GC data. Then, the background level is subtracted from the image, producing a chromatogram in which the peaks rise above a near-zero mean background. After the background level is removed, further analysis is required to determine the quantitative relationship between the peaks and chemicals in the sample. The algorithm is demonstrated experimentally to be effective at determining and removing the background level from GC×GC images. The algorithm has several parametric controls and is incorporated into an interactive program with graphical interface for rapid and accurate detection of GC×GC peaks.

AB - This paper describes a new technique for removing the background level from digital images produced in comprehensive two-dimensional gas chromatography (GC×GC). Background removal is an important first step in the larger problem of quantitative analysis. The approach estimates the background level across the chromatographic image based on structural and statistical properties of GC×GC data. Then, the background level is subtracted from the image, producing a chromatogram in which the peaks rise above a near-zero mean background. After the background level is removed, further analysis is required to determine the quantitative relationship between the peaks and chemicals in the sample. The algorithm is demonstrated experimentally to be effective at determining and removing the background level from GC×GC images. The algorithm has several parametric controls and is incorporated into an interactive program with graphical interface for rapid and accurate detection of GC×GC peaks.

KW - Gas chromatography, comprehensive two-dimensional

KW - Image background removal

UR - http://www.scopus.com/inward/record.url?scp=0037462515&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037462515&partnerID=8YFLogxK

U2 - 10.1016/S0021-9673(02)01498-X

DO - 10.1016/S0021-9673(02)01498-X

M3 - Article

C2 - 12580469

AN - SCOPUS:0037462515

VL - 985

SP - 47

EP - 56

JO - Journal of Chromatography A

JF - Journal of Chromatography A

SN - 0021-9673

IS - 1-2

ER -