Identification of LytSR-regulated genes from Staphylococcus aureus

Eric W. Brunskill, Kenneth W Bayles

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

In this report, the characterization of a Staphylococcus aureus operon containing two LytSR-regulated genes, lrgA and lrgB, is described. Sequence and mutagenesis studies of these genes suggest that lrgA encodes a murein hydrolase exporter similar to bacteriophage holin proteins while lrgB may encode a protein having murein hydrolase activity.

Original languageEnglish (US)
Pages (from-to)5810-5812
Number of pages3
JournalJournal of bacteriology
Volume178
Issue number19
DOIs
StatePublished - Jan 1 1996

Fingerprint

N-Acetylmuramoyl-L-alanine Amidase
Staphylococcus aureus
Operon
Mutagenesis
Bacteriophages
Genes
Proteins

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

Cite this

Identification of LytSR-regulated genes from Staphylococcus aureus. / Brunskill, Eric W.; Bayles, Kenneth W.

In: Journal of bacteriology, Vol. 178, No. 19, 01.01.1996, p. 5810-5812.

Research output: Contribution to journalArticle

@article{e38716e54ef54572ae27e8d20f1d4627,
title = "Identification of LytSR-regulated genes from Staphylococcus aureus",
abstract = "In this report, the characterization of a Staphylococcus aureus operon containing two LytSR-regulated genes, lrgA and lrgB, is described. Sequence and mutagenesis studies of these genes suggest that lrgA encodes a murein hydrolase exporter similar to bacteriophage holin proteins while lrgB may encode a protein having murein hydrolase activity.",
author = "Brunskill, {Eric W.} and Bayles, {Kenneth W}",
year = "1996",
month = "1",
day = "1",
doi = "10.1128/jb.178.19.5810-5812.1996",
language = "English (US)",
volume = "178",
pages = "5810--5812",
journal = "Journal of Bacteriology",
issn = "0021-9193",
publisher = "American Society for Microbiology",
number = "19",

}

TY - JOUR

T1 - Identification of LytSR-regulated genes from Staphylococcus aureus

AU - Brunskill, Eric W.

AU - Bayles, Kenneth W

PY - 1996/1/1

Y1 - 1996/1/1

N2 - In this report, the characterization of a Staphylococcus aureus operon containing two LytSR-regulated genes, lrgA and lrgB, is described. Sequence and mutagenesis studies of these genes suggest that lrgA encodes a murein hydrolase exporter similar to bacteriophage holin proteins while lrgB may encode a protein having murein hydrolase activity.

AB - In this report, the characterization of a Staphylococcus aureus operon containing two LytSR-regulated genes, lrgA and lrgB, is described. Sequence and mutagenesis studies of these genes suggest that lrgA encodes a murein hydrolase exporter similar to bacteriophage holin proteins while lrgB may encode a protein having murein hydrolase activity.

UR - http://www.scopus.com/inward/record.url?scp=0029835932&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029835932&partnerID=8YFLogxK

U2 - 10.1128/jb.178.19.5810-5812.1996

DO - 10.1128/jb.178.19.5810-5812.1996

M3 - Article

VL - 178

SP - 5810

EP - 5812

JO - Journal of Bacteriology

JF - Journal of Bacteriology

SN - 0021-9193

IS - 19

ER -