Identification of a fragmented small GTPase capable of conditional effector binding

Research output: Contribution to journalArticle

Abstract

A fragmented small GTPase capable of conditional effector binding is described. The effector binding function of this split-GTPase can be modulated using a small molecule input, thus allowing for the potential design of cellular signaling pathways.

Original languageEnglish (US)
Pages (from-to)12265-12268
Number of pages4
JournalRSC Advances
Volume7
Issue number20
DOIs
StatePublished - Jan 1 2017

Fingerprint

Cell signaling
Monomeric GTP-Binding Proteins
GTP Phosphohydrolases
Molecules

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Identification of a fragmented small GTPase capable of conditional effector binding. / Zhao, Jia; Stains, Clifford I.

In: RSC Advances, Vol. 7, No. 20, 01.01.2017, p. 12265-12268.

Research output: Contribution to journalArticle

@article{b040108963ed4d92ab8ef262676a2285,
title = "Identification of a fragmented small GTPase capable of conditional effector binding",
abstract = "A fragmented small GTPase capable of conditional effector binding is described. The effector binding function of this split-GTPase can be modulated using a small molecule input, thus allowing for the potential design of cellular signaling pathways.",
author = "Jia Zhao and Stains, {Clifford I}",
year = "2017",
month = "1",
day = "1",
doi = "10.1039/c6ra25575b",
language = "English (US)",
volume = "7",
pages = "12265--12268",
journal = "RSC Advances",
issn = "2046-2069",
publisher = "Royal Society of Chemistry",
number = "20",

}

TY - JOUR

T1 - Identification of a fragmented small GTPase capable of conditional effector binding

AU - Zhao, Jia

AU - Stains, Clifford I

PY - 2017/1/1

Y1 - 2017/1/1

N2 - A fragmented small GTPase capable of conditional effector binding is described. The effector binding function of this split-GTPase can be modulated using a small molecule input, thus allowing for the potential design of cellular signaling pathways.

AB - A fragmented small GTPase capable of conditional effector binding is described. The effector binding function of this split-GTPase can be modulated using a small molecule input, thus allowing for the potential design of cellular signaling pathways.

UR - http://www.scopus.com/inward/record.url?scp=85013660848&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85013660848&partnerID=8YFLogxK

U2 - 10.1039/c6ra25575b

DO - 10.1039/c6ra25575b

M3 - Article

AN - SCOPUS:85013660848

VL - 7

SP - 12265

EP - 12268

JO - RSC Advances

JF - RSC Advances

SN - 2046-2069

IS - 20

ER -