Hypersensitivity reactions to deoxycoformycin

Peter J. O'Dwyer, Susan A. King, Elizabeth Eisenhauer, Jean L. Grem, Daniel F. Hoth

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Deoxycoformycin (dCF) is a promising new antineoplastic agent in the treatment of lymphoid malignancies, particularly hairy cell leukemia (HCL). Skin toxicity in the form of a maculopapular eruption has previously been reported but has not clearly been associated with idiosyncratic reactions. We present five cases of dCF-related hypersensitivity reactions in which additional systemic manifestations indicated an allergic etiology. The value of dCF in treating lymphoid neoplasms suggests that further study of the treatment of these reactions is indicated.

Original languageEnglish (US)
Pages (from-to)173-175
Number of pages3
JournalCancer Chemotherapy and Pharmacology
Volume23
Issue number3
DOIs
Publication statusPublished - Mar 1 1989

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ASJC Scopus subject areas

  • Oncology
  • Toxicology
  • Pharmacology
  • Cancer Research
  • Pharmacology (medical)

Cite this

O'Dwyer, P. J., King, S. A., Eisenhauer, E., Grem, J. L., & Hoth, D. F. (1989). Hypersensitivity reactions to deoxycoformycin. Cancer Chemotherapy and Pharmacology, 23(3), 173-175. https://doi.org/10.1007/BF00267950