Hydrogel Templates for Rapid Manufacturing of Bioactive Fibers and 3D Constructs

Ali Tamayol, Alireza Hassani Najafabadi, Bahar Aliakbarian, Elmira Arab-Tehrany, Mohsen Akbari, Nasim Annabi, David Juncker, Ali Khademhosseini

Research output: Contribution to journalArticle

71 Scopus citations


Hydrogel templates are formed to entrap various pre-polymers prior to their crosslinking process. Upon the completion of the crosslinking process, an independent polymer network with the same fiber geometry is formed. The hydrogel template can be removed if necessary. As the proof-of-principle, fibers from various polymers are fabricated. The fabricated hybrid polymeric fibers are bioactive and can be bioprinted or assembled using textile processes. The approach can be used for creating complex 3D constructs for various applications.

Original languageEnglish (US)
Pages (from-to)2146-2153
Number of pages8
JournalAdvanced Healthcare Materials
Issue number14
StatePublished - Oct 7 2015



  • Bioprinting
  • Cell-laden fibers
  • Fiber-based methods
  • Sacrificial polymeric networks
  • Tissue engineering

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Pharmaceutical Science

Cite this

Tamayol, A., Najafabadi, A. H., Aliakbarian, B., Arab-Tehrany, E., Akbari, M., Annabi, N., Juncker, D., & Khademhosseini, A. (2015). Hydrogel Templates for Rapid Manufacturing of Bioactive Fibers and 3D Constructs. Advanced Healthcare Materials, 4(14), 2146-2153. https://doi.org/10.1002/adhm.201500492