Human herpesvirus 8 as a potential sexually transmitted agent in honduras

C. Sosa, W. Klaskala, B. Chandran, R. Soto, L. Sieczkowski, M. H. Wu, M. Baum, Charles Wood

Research output: Contribution to journalArticle

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Abstract

The seroprevalence of human herpesvirus 8 (HHV-8) was studied in 326 human immunodeficiency virus (HIV)-positive and -negative persons from Honduras; women constituted 77% (n = 251) of the subjects. Sera were tested for lytic HHV-8 antibodies by an IFA, and positive samples were confirmed by a radioimmunoprecipitation assay. Of the 326 persons tested, 58 (17.8%) had HHV-8 antibodies. Among the HIV-infected women, 22.7% were seropositive; 11.3% of the HIV-negative women were seropositive. HHV-8 seroprevalence was almost four times higher in HIV-positive female commercial sex workers (36%) than in HIV-negative female non-commercial sex workers (9.9%; odds ratio = 3.8, 95% confidence interval = 1.1-13; P = 0.01), suggesting that commercial sex work is a risk factor for HHV-8 infection. In the men studied, the overall HHV-8 seroprevalence was 22.6%, with a seropositivity rate of 28% for HIV-positive men compared with 12% for HIV-negative men.

Original languageEnglish (US)
Pages (from-to)547-551
Number of pages5
JournalJournal of Infectious Diseases
Volume178
Issue number2
DOIs
StatePublished - Jan 1 1998

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Honduras
Human Herpesvirus 8
HIV
Seroepidemiologic Studies
Sex Workers
Radioimmunoprecipitation Assay
Sex Work
Herpesviridae Infections
Antibodies
Odds Ratio
Confidence Intervals

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

Cite this

Sosa, C., Klaskala, W., Chandran, B., Soto, R., Sieczkowski, L., Wu, M. H., ... Wood, C. (1998). Human herpesvirus 8 as a potential sexually transmitted agent in honduras. Journal of Infectious Diseases, 178(2), 547-551. https://doi.org/10.1086/517471

Human herpesvirus 8 as a potential sexually transmitted agent in honduras. / Sosa, C.; Klaskala, W.; Chandran, B.; Soto, R.; Sieczkowski, L.; Wu, M. H.; Baum, M.; Wood, Charles.

In: Journal of Infectious Diseases, Vol. 178, No. 2, 01.01.1998, p. 547-551.

Research output: Contribution to journalArticle

Sosa, C, Klaskala, W, Chandran, B, Soto, R, Sieczkowski, L, Wu, MH, Baum, M & Wood, C 1998, 'Human herpesvirus 8 as a potential sexually transmitted agent in honduras', Journal of Infectious Diseases, vol. 178, no. 2, pp. 547-551. https://doi.org/10.1086/517471
Sosa C, Klaskala W, Chandran B, Soto R, Sieczkowski L, Wu MH et al. Human herpesvirus 8 as a potential sexually transmitted agent in honduras. Journal of Infectious Diseases. 1998 Jan 1;178(2):547-551. https://doi.org/10.1086/517471
Sosa, C. ; Klaskala, W. ; Chandran, B. ; Soto, R. ; Sieczkowski, L. ; Wu, M. H. ; Baum, M. ; Wood, Charles. / Human herpesvirus 8 as a potential sexually transmitted agent in honduras. In: Journal of Infectious Diseases. 1998 ; Vol. 178, No. 2. pp. 547-551.
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