Host factors against plant viruses

Research output: Contribution to journalReview article

Abstract

Plant virus genome replication and movement is dependent on host resources and factors. However, plants respond to virus infection through several mechanisms, such as autophagy, ubiquitination, mRNA decay and gene silencing, that target viral components. Viral factors work in synchrony with pro-viral host factors during the infection cycle and are targeted by antiviral responses. Accordingly, establishment of virus infection is genetically determined by the availability of the pro-viral factors necessary for genome replication and movement, and by the balance between plant defence and viral suppression of defence responses. Sequential requirement of pro-viral factors and the antagonistic activity of antiviral factors suggest a two-step model to explain plant–virus interactions. At each step of the infection process, host factors with antiviral activity have been identified. Here we review our current understanding of host factors with antiviral activity against plant viruses.

Original languageEnglish (US)
Pages (from-to)1588-1601
Number of pages14
JournalMolecular Plant Pathology
Volume20
Issue number11
DOIs
StatePublished - Nov 1 2019

Fingerprint

Plant Viruses
plant viruses
Antiviral Agents
virus
Virus Diseases
infection
genome
Plant Genome
Viral Structures
viruses
plant defense
autophagy
Ubiquitination
synchrony
Autophagy
RNA Stability
Gene Silencing
gene silencing
Virus Replication
Infection

Keywords

  • antiviral defence
  • host factors
  • virus resistance
  • virus–host interactions

ASJC Scopus subject areas

  • Molecular Biology
  • Agronomy and Crop Science
  • Soil Science
  • Plant Science

Cite this

Host factors against plant viruses. / Garcia-Ruiz, Hernan.

In: Molecular Plant Pathology, Vol. 20, No. 11, 01.11.2019, p. 1588-1601.

Research output: Contribution to journalReview article

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