Histological evaluation of chronically implanted tissue-engineered-electronic-neural-interface (TEENI) devices

James B. Graham, Eric W. Atkinson, Elizabeth A. Nunamaker, Benjamin S. Spearman, Vidhi H. Desai, Chancellor S. Shafor, Sruthi Natt, Rebecca A. Wachs, Christine E. Schmidt, Jack W. Judy, Kevin J. Otto

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Neural-interface devices have the potential to isolate and transduce both afferent (sensory) and efferent (motor) neural signals of the peripheral nerve to and from electrical signals in instrumentation for stimulation and recording to produce fine control of advanced prosthetics. In order to potentiate the full spectrum of possible applications, the persistent foreign-body response needs to be addressed. Here we describe the cellular and extracellular components of chronically implanted polyimide threads suspended within a tricomponent hydrogel. The results of these experiments will contribute to design modifications for future fabrications of tissue-engineered-electronic-nerve-interface (TEENI) devices.

Original languageEnglish (US)
Title of host publication8th International IEEE EMBS Conference on Neural Engineering, NER 2017
PublisherIEEE Computer Society
Pages275-278
Number of pages4
ISBN (Electronic)9781538619162
DOIs
Publication statusPublished - Aug 10 2017
Event8th International IEEE EMBS Conference on Neural Engineering, NER 2017 - Shanghai, China
Duration: May 25 2017May 28 2017

Publication series

NameInternational IEEE/EMBS Conference on Neural Engineering, NER
ISSN (Print)1948-3546
ISSN (Electronic)1948-3554

Other

Other8th International IEEE EMBS Conference on Neural Engineering, NER 2017
CountryChina
CityShanghai
Period5/25/175/28/17

    Fingerprint

ASJC Scopus subject areas

  • Artificial Intelligence
  • Mechanical Engineering

Cite this

Graham, J. B., Atkinson, E. W., Nunamaker, E. A., Spearman, B. S., Desai, V. H., Shafor, C. S., ... Otto, K. J. (2017). Histological evaluation of chronically implanted tissue-engineered-electronic-neural-interface (TEENI) devices. In 8th International IEEE EMBS Conference on Neural Engineering, NER 2017 (pp. 275-278). [8008344] (International IEEE/EMBS Conference on Neural Engineering, NER). IEEE Computer Society. https://doi.org/10.1109/NER.2017.8008344