Histological characteristics associated with suppurating periodontal pockets.

S. A. Passo, Richard A Reinhardt, L. M. DuBois, D. M. Cohen

Research output: Contribution to journalArticle

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Abstract

The purpose of this study was to characterize histologically the gingival lesion associated with suppuration in advanced periodontitis. Thirty-three bleeding, suppurating (S) and 23 bleeding, nonsuppurating (NS) interproximal biopsies were obtained from nine patients and processed for light microscopy. Pocket depths (mean +/- SD) were 6.7 +/- 1.6 mm (S) and 5.4 +/- 2.2 mm (NS). Six-micron serial sections were stained with (1) hematoxylin/eosin and (2) van Gieson. Quantitative cell types were determined by a grid intersection counting technique at x 1000. Volumetric analysis of collagen-poor (inflammation) areas was conducted using a computer biometric system that revealed three histologic patterns: Type I sites showed mild to moderate inflammation (less than 50% infiltrate, S = 15, NS = 20); Type II sites showed intense inflammation (greater than 50% infiltrate, S = 17, NS = 3); and only one (S) site had a large connective tissue abscess (Type III). The mean percentage of collagen-poor area was significantly larger in suppurating (42.1 +/- 25.5%) versus nonsuppurating (27.7 +/- 20.4%) sites (P = 0.02). In both S and NS sites, plasma cells (means = 66%) and lymphocytes (means = 27%) predominated in the inflammatory infiltrates. Histologically, suppuration appeared to be associated with increased gingival inflammation and a slight increase in connective tissue neutrophils.

Original languageEnglish (US)
Pages (from-to)731-740
Number of pages10
JournalJournal of periodontology
Volume59
Issue number11
DOIs
StatePublished - Jan 1 1988

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Periodontal Pocket
Inflammation
Suppuration
Connective Tissue
Collagen
Hemorrhage
Periodontitis
Computer Systems
Hematoxylin
Eosine Yellowish-(YS)
Plasma Cells
Abscess
Microscopy
Neutrophils
Lymphocytes
Biopsy
Light

ASJC Scopus subject areas

  • Periodontics

Cite this

Histological characteristics associated with suppurating periodontal pockets. / Passo, S. A.; Reinhardt, Richard A; DuBois, L. M.; Cohen, D. M.

In: Journal of periodontology, Vol. 59, No. 11, 01.01.1988, p. 731-740.

Research output: Contribution to journalArticle

Passo, S. A. ; Reinhardt, Richard A ; DuBois, L. M. ; Cohen, D. M. / Histological characteristics associated with suppurating periodontal pockets. In: Journal of periodontology. 1988 ; Vol. 59, No. 11. pp. 731-740.
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