Histiocytic lymphoma and malignant angioendotheliomatosis. One disease or two?

Jack Ansell, Jag Bhawan, Samuel Monroe Cohen, John Sullivan, David Sherman

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

The case history of a patient with diffuse histiocytic lymphoma and skin lesions characteristic of malignant angioendotheliomatosis is reported. The patient initially responded to aggressive chemotherapy but quickly had a relapse, CNS disease developed, and the patient died one year after diagnosis. Microscopic, ultrastructural, and surface membrane studies showed that the intravascular tumor cells were not of endothelial origin. The morphologic similarity of the malignant intravascular cells and peripheral blood cells, as well as the demonstration of surface membrane immunoglobulin on malignant blood cells suggested that, in some cases, unusual features of malignant lymphoma may be confused with malignant angioendotheliomatosis.

Original languageEnglish (US)
Pages (from-to)1506-1512
Number of pages7
JournalCancer
Volume50
Issue number8
DOIs
StatePublished - Jan 1 1982

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Lymphoma, Large B-Cell, Diffuse
Blood Cells
B-Cell Antigen Receptors
Membranes
Central Nervous System Diseases
Lymphoma
Recurrence
Drug Therapy
Skin
Neoplasms

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Histiocytic lymphoma and malignant angioendotheliomatosis. One disease or two? / Ansell, Jack; Bhawan, Jag; Cohen, Samuel Monroe; Sullivan, John; Sherman, David.

In: Cancer, Vol. 50, No. 8, 01.01.1982, p. 1506-1512.

Research output: Contribution to journalArticle

Ansell, Jack ; Bhawan, Jag ; Cohen, Samuel Monroe ; Sullivan, John ; Sherman, David. / Histiocytic lymphoma and malignant angioendotheliomatosis. One disease or two?. In: Cancer. 1982 ; Vol. 50, No. 8. pp. 1506-1512.
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