Hippocampal Transections for Epilepsy

Arun Angelo Patil, Andrea Jennifer Chamczuk, Richard V. Andrews

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Multiple hippocampal transection (MHT) is a novel surgical procedure that serves to disrupt seizure propagation fibers within the hippocampus without impairing verbal memory or the loss of stem cells. Given the paucity of literature regarding the utility and long-term outcome of MHT, a review is presented of the current literature to support the utility of this procedure in the treatment of intractable temporal lobe epilepsy. Long-term outcome analysis of this technique has been reported by 2 independent groups. Both groups used intraoperative electrocorticography. All patients underwent multiple subpial transection on the neocortex and MHT on the hippocampus.

Original languageEnglish (US)
Pages (from-to)19-25
Number of pages7
JournalNeurosurgery Clinics of North America
Volume27
Issue number1
DOIs
StatePublished - Jan 1 2016

Fingerprint

Epilepsy
Hippocampus
Temporal Lobe Epilepsy
Neocortex
Memory Disorders
Seizures
Stem Cells
Therapeutics
Electrocorticography
Drug Resistant Epilepsy

Keywords

  • Long-term outcome
  • Multiple hippocampal transection
  • Temporal lobe epilepsy
  • Verbal memory

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Hippocampal Transections for Epilepsy. / Patil, Arun Angelo; Chamczuk, Andrea Jennifer; Andrews, Richard V.

In: Neurosurgery Clinics of North America, Vol. 27, No. 1, 01.01.2016, p. 19-25.

Research output: Contribution to journalReview article

Patil, AA, Chamczuk, AJ & Andrews, RV 2016, 'Hippocampal Transections for Epilepsy', Neurosurgery Clinics of North America, vol. 27, no. 1, pp. 19-25. https://doi.org/10.1016/j.nec.2015.08.013
Patil, Arun Angelo ; Chamczuk, Andrea Jennifer ; Andrews, Richard V. / Hippocampal Transections for Epilepsy. In: Neurosurgery Clinics of North America. 2016 ; Vol. 27, No. 1. pp. 19-25.
@article{eb39af785bc14401861ba64dc3935799,
title = "Hippocampal Transections for Epilepsy",
abstract = "Multiple hippocampal transection (MHT) is a novel surgical procedure that serves to disrupt seizure propagation fibers within the hippocampus without impairing verbal memory or the loss of stem cells. Given the paucity of literature regarding the utility and long-term outcome of MHT, a review is presented of the current literature to support the utility of this procedure in the treatment of intractable temporal lobe epilepsy. Long-term outcome analysis of this technique has been reported by 2 independent groups. Both groups used intraoperative electrocorticography. All patients underwent multiple subpial transection on the neocortex and MHT on the hippocampus.",
keywords = "Long-term outcome, Multiple hippocampal transection, Temporal lobe epilepsy, Verbal memory",
author = "Patil, {Arun Angelo} and Chamczuk, {Andrea Jennifer} and Andrews, {Richard V.}",
year = "2016",
month = "1",
day = "1",
doi = "10.1016/j.nec.2015.08.013",
language = "English (US)",
volume = "27",
pages = "19--25",
journal = "Neurosurgery Clinics of North America",
issn = "1042-3680",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Hippocampal Transections for Epilepsy

AU - Patil, Arun Angelo

AU - Chamczuk, Andrea Jennifer

AU - Andrews, Richard V.

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Multiple hippocampal transection (MHT) is a novel surgical procedure that serves to disrupt seizure propagation fibers within the hippocampus without impairing verbal memory or the loss of stem cells. Given the paucity of literature regarding the utility and long-term outcome of MHT, a review is presented of the current literature to support the utility of this procedure in the treatment of intractable temporal lobe epilepsy. Long-term outcome analysis of this technique has been reported by 2 independent groups. Both groups used intraoperative electrocorticography. All patients underwent multiple subpial transection on the neocortex and MHT on the hippocampus.

AB - Multiple hippocampal transection (MHT) is a novel surgical procedure that serves to disrupt seizure propagation fibers within the hippocampus without impairing verbal memory or the loss of stem cells. Given the paucity of literature regarding the utility and long-term outcome of MHT, a review is presented of the current literature to support the utility of this procedure in the treatment of intractable temporal lobe epilepsy. Long-term outcome analysis of this technique has been reported by 2 independent groups. Both groups used intraoperative electrocorticography. All patients underwent multiple subpial transection on the neocortex and MHT on the hippocampus.

KW - Long-term outcome

KW - Multiple hippocampal transection

KW - Temporal lobe epilepsy

KW - Verbal memory

UR - http://www.scopus.com/inward/record.url?scp=84950253018&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84950253018&partnerID=8YFLogxK

U2 - 10.1016/j.nec.2015.08.013

DO - 10.1016/j.nec.2015.08.013

M3 - Review article

C2 - 26615104

AN - SCOPUS:84950253018

VL - 27

SP - 19

EP - 25

JO - Neurosurgery Clinics of North America

JF - Neurosurgery Clinics of North America

SN - 1042-3680

IS - 1

ER -