High-Resolution Solid-State NMR Applied to Polypeptides and Membrane Proteins

Sorin M Luca, Henrike Heise, Marc Baldus

Research output: Contribution to journalReview article

88 Citations (Scopus)

Abstract

Solid-state NMR provides unique possibilities to study insoluble or noncrystalline molecules at the atomic level. High-resolution conditions can be established by employing magic-angle spinning at ultrahigh magnetic fields. We discuss NMR methods that make use of these experimental improvements and allow for the study of multiply or uniformly 13C,15N]-labeled polypeptides and proteins. Recent biophysical applications are reviewed.

Original languageEnglish (US)
Pages (from-to)858-865
Number of pages8
JournalAccounts of Chemical Research
Volume36
Issue number11
DOIs
StatePublished - Nov 1 2003

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Membrane Proteins
Nuclear magnetic resonance
Peptides
Magic angle spinning
Magnetic fields
Molecules
Proteins

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

High-Resolution Solid-State NMR Applied to Polypeptides and Membrane Proteins. / Luca, Sorin M; Heise, Henrike; Baldus, Marc.

In: Accounts of Chemical Research, Vol. 36, No. 11, 01.11.2003, p. 858-865.

Research output: Contribution to journalReview article

Luca, Sorin M ; Heise, Henrike ; Baldus, Marc. / High-Resolution Solid-State NMR Applied to Polypeptides and Membrane Proteins. In: Accounts of Chemical Research. 2003 ; Vol. 36, No. 11. pp. 858-865.
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