Heritable connective tissue disorders in cervical artery dissections: A prospective study

W. I. Schievink, E. F M Wijdicks, V. V. Michels, J. Vockley, Maurice Godfrey

Research output: Contribution to journalArticle

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Abstract

We prospectively evaluated 15 consecutive patients with spontaneous cervical artery dissections. Three patients (20%) had a heritable connective tissue disorder, each with a unique phenotype. None of these patients met the criteria of any of the named syndromes, and collagen and fibrillin analyses were normal. Heritable connective tissue disorders are common among patients with spontaneous cervical artery dissections, but, despite intensive investigations, the type of disorder usually cannot be identified. The underlying arteriopathy in cervical artery dissections is likely to be heterogeneous.

Original languageEnglish (US)
Pages (from-to)1166-1169
Number of pages4
JournalNeurology
Volume50
Issue number4
DOIs
StatePublished - Apr 1998

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Connective Tissue
Dissection
Arteries
Prospective Studies
Collagen
Phenotype

ASJC Scopus subject areas

  • Clinical Neurology

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Heritable connective tissue disorders in cervical artery dissections : A prospective study. / Schievink, W. I.; Wijdicks, E. F M; Michels, V. V.; Vockley, J.; Godfrey, Maurice.

In: Neurology, Vol. 50, No. 4, 04.1998, p. 1166-1169.

Research output: Contribution to journalArticle

Schievink, W. I. ; Wijdicks, E. F M ; Michels, V. V. ; Vockley, J. ; Godfrey, Maurice. / Heritable connective tissue disorders in cervical artery dissections : A prospective study. In: Neurology. 1998 ; Vol. 50, No. 4. pp. 1166-1169.
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