Hepatosplenic γ-δ T-Cell Lymphoma: Who Is on Your Speed Dial?

Mridula Krishnan, Matthew Lunning

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Hepatosplenic γ-δ T-cell lymphoma, an exceptionally uncommon subtype of peripheral T-cell lymphomas, commonly presents with advanced-stage disease manifesting with hepatosplenomegaly, cytopenias, and constitutional symptoms. Management of this subset is challenging as a result of the unique presentation and refractory nature to conventional treatment approaches. There is a lack of consensus guidelines for up-front induction strategies, and the role of consolidative autologous or allogeneic stem-cell transplantation is controversial. Prospective studies are lacking, and treatment is often guided by literature on the basis of case series or single-institution studies, lending to expert opinions influencing treatment paradigms.

Original languageEnglish (US)
Pages (from-to)307-312
Number of pages6
JournalJournal of oncology practice
Volume15
Issue number6
DOIs
StatePublished - Jun 1 2019

Fingerprint

T-Cell Lymphoma
Peripheral T-Cell Lymphoma
Expert Testimony
Stem Cell Transplantation
Therapeutics
Prospective Studies
Guidelines

ASJC Scopus subject areas

  • Oncology
  • Oncology(nursing)
  • Health Policy

Cite this

Hepatosplenic γ-δ T-Cell Lymphoma : Who Is on Your Speed Dial? / Krishnan, Mridula; Lunning, Matthew.

In: Journal of oncology practice, Vol. 15, No. 6, 01.06.2019, p. 307-312.

Research output: Contribution to journalArticle

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