Hepatitis-C prevalence in an urban native-American clinic

A prospective screening study

Amy S Neumeister, LaVada E. Pilcher, Judi M. Erickson, Lora L. Langley, Mary M. Murphy, Nicole M. Haukaas, Mark E Mailliard, Jennifer Lynn Larsen

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background: Native-American populations are disproportionately burdened by chronic liver disease, and the prevalence of hepatitis C (HCV) in native Americans is unknown. Purpose: To determine the prevalence of hepatitis C in a local native-American population via a prospective screening study. Procedures: Two-hundred-forty-three native Americans (161 females/82 males) using an urban clinic and representing >30 tribes from across the United States were screened. Mean age was 41 ± 1 years. Hepatitis-C screening was by anti-HCV with confirmation by HCV RNA. A questionnaire assessed potential risk factors for HCV. Findings: Anti-HCV antibodies were found in 11.5% (95% CI: 7.5-15.5%). HCV RNA was present by polymerase chain reaction (PCR) in 8.6% (95% CI: 5.1-12.1%) and was more common in males [13.4% (95% CI: 6.0-20.8%)] than females [6.2% (95% CI: 2.5-9.9%)]. The most common potential risk factors for chronic HCV infection were intravenous (IV) drug or cocaine use (p<0.0001), tattoos >5 years old (p<0.0001) and having a sexual partner with HCV (p=0.0063). Conclusion: HCV prevalence is higher in an urban native-American clinic population than reported in the general U.S. population. Use of IV drugs is the most prevalent risk factor, but tattoos and sexual transmission may also be important.

Original languageEnglish (US)
Pages (from-to)389-392
Number of pages4
JournalJournal of the National Medical Association
Volume99
Issue number4
StatePublished - Apr 1 2007

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North American Indians
Hepatitis C
Prospective Studies
Population
RNA
Hepatitis C Antibodies
Sexual Partners
Cocaine
Population Groups
Pharmaceutical Preparations
Liver Diseases
Chronic Disease
Polymerase Chain Reaction
Infection

Keywords

  • Hepatitis
  • Native Americans

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hepatitis-C prevalence in an urban native-American clinic : A prospective screening study. / Neumeister, Amy S; Pilcher, LaVada E.; Erickson, Judi M.; Langley, Lora L.; Murphy, Mary M.; Haukaas, Nicole M.; Mailliard, Mark E; Larsen, Jennifer Lynn.

In: Journal of the National Medical Association, Vol. 99, No. 4, 01.04.2007, p. 389-392.

Research output: Contribution to journalArticle

Neumeister AS, Pilcher LE, Erickson JM, Langley LL, Murphy MM, Haukaas NM et al. Hepatitis-C prevalence in an urban native-American clinic: A prospective screening study. Journal of the National Medical Association. 2007 Apr 1;99(4):389-392.
Neumeister, Amy S ; Pilcher, LaVada E. ; Erickson, Judi M. ; Langley, Lora L. ; Murphy, Mary M. ; Haukaas, Nicole M. ; Mailliard, Mark E ; Larsen, Jennifer Lynn. / Hepatitis-C prevalence in an urban native-American clinic : A prospective screening study. In: Journal of the National Medical Association. 2007 ; Vol. 99, No. 4. pp. 389-392.
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