Abstract

Hematopoietic stem cell transplantation has become increasingly important in the treatment of hematologic malignancies over the past 20 years. While it is associated with significant morbidity, it offers the only chance of cure in many circumstances. Autologous and allogeneic transplantation have been used successfully to treat a variety of hematologic malignancies. These 2 approaches offer different risks and benefits which are discussed in this review. Timing of transplantation and selection of patients are also discussed. New innovations in stem cell transplantation including umbilical cord blood and non-myeloablative transplantation are reviewed.

Original languageEnglish (US)
Pages (from-to)61-74
Number of pages14
JournalPanminerva Medica
Volume46
Issue number1
StatePublished - Mar 1 2004

Fingerprint

Hematopoietic Stem Cell Transplantation
Hematologic Neoplasms
Cord Blood Stem Cell Transplantation
Transplantation
Autologous Transplantation
Homologous Transplantation
Patient Selection
Morbidity
Therapeutics

Keywords

  • Hematopoietic stem cells
  • Hematopoietic stem cells transplantation
  • Stem cells

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hematopoietic stem cell transplantation in hematologic malignancy. / Archuleta, T. D.; DeVetten, Marcel P; Armitage, James Olen.

In: Panminerva Medica, Vol. 46, No. 1, 01.03.2004, p. 61-74.

Research output: Contribution to journalReview article

@article{1ad6a534376c46bf99f217c9131b4ad6,
title = "Hematopoietic stem cell transplantation in hematologic malignancy",
abstract = "Hematopoietic stem cell transplantation has become increasingly important in the treatment of hematologic malignancies over the past 20 years. While it is associated with significant morbidity, it offers the only chance of cure in many circumstances. Autologous and allogeneic transplantation have been used successfully to treat a variety of hematologic malignancies. These 2 approaches offer different risks and benefits which are discussed in this review. Timing of transplantation and selection of patients are also discussed. New innovations in stem cell transplantation including umbilical cord blood and non-myeloablative transplantation are reviewed.",
keywords = "Hematopoietic stem cells, Hematopoietic stem cells transplantation, Stem cells",
author = "Archuleta, {T. D.} and DeVetten, {Marcel P} and Armitage, {James Olen}",
year = "2004",
month = "3",
day = "1",
language = "English (US)",
volume = "46",
pages = "61--74",
journal = "Panminerva Medica",
issn = "0031-0808",
publisher = "Edizioni Minerva Medica S.p.A.",
number = "1",

}

TY - JOUR

T1 - Hematopoietic stem cell transplantation in hematologic malignancy

AU - Archuleta, T. D.

AU - DeVetten, Marcel P

AU - Armitage, James Olen

PY - 2004/3/1

Y1 - 2004/3/1

N2 - Hematopoietic stem cell transplantation has become increasingly important in the treatment of hematologic malignancies over the past 20 years. While it is associated with significant morbidity, it offers the only chance of cure in many circumstances. Autologous and allogeneic transplantation have been used successfully to treat a variety of hematologic malignancies. These 2 approaches offer different risks and benefits which are discussed in this review. Timing of transplantation and selection of patients are also discussed. New innovations in stem cell transplantation including umbilical cord blood and non-myeloablative transplantation are reviewed.

AB - Hematopoietic stem cell transplantation has become increasingly important in the treatment of hematologic malignancies over the past 20 years. While it is associated with significant morbidity, it offers the only chance of cure in many circumstances. Autologous and allogeneic transplantation have been used successfully to treat a variety of hematologic malignancies. These 2 approaches offer different risks and benefits which are discussed in this review. Timing of transplantation and selection of patients are also discussed. New innovations in stem cell transplantation including umbilical cord blood and non-myeloablative transplantation are reviewed.

KW - Hematopoietic stem cells

KW - Hematopoietic stem cells transplantation

KW - Stem cells

UR - http://www.scopus.com/inward/record.url?scp=4143087120&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4143087120&partnerID=8YFLogxK

M3 - Review article

VL - 46

SP - 61

EP - 74

JO - Panminerva Medica

JF - Panminerva Medica

SN - 0031-0808

IS - 1

ER -