Health care-associated infections in the neonatal intensive care unit, a review of impact, risk factors, and prevention strategies

Research output: Contribution to journalArticle

Abstract

Nosocomial infection or health care-associated infection (HAI) causes significant morbidity and mortality in the neonatal intensive care unit (NICU) population. Associated risk factors include low birth weight, indwelling central catheter, parenteral nutrition, prior antibiotic exposure, and invasive procedures, all of which are common in the NICU setting. Decreasing rates and minimizing risk is a priority for hospital caregivers; however, rates vary widely from center to center. This review article discusses the reported rates of HAI and central line-associated bloodstream infection in the NICU population and reviews risk factors, physical examination findings, laboratory evaluation, causative organisms, and therapies (both antimicrobial and supportive). A review and summary of interventions, which have been proven successful in reducing HAI and central line-associated bloodstream infection in the NICU patient population, is included.

Original languageEnglish (US)
Pages (from-to)187-194
Number of pages8
JournalNewborn and Infant Nursing Reviews
Volume10
Issue number4
DOIs
StatePublished - Dec 1 2010

Fingerprint

Neonatal Intensive Care Units
Cross Infection
Population
Indwelling Catheters
Parenteral Nutrition
Low Birth Weight Infant
Infection
Caregivers
Physical Examination
Anti-Bacterial Agents
Morbidity
Mortality
Therapeutics

Keywords

  • Catheter-associated bloodstream infection
  • Health care-associated infection
  • NICU
  • Neonate
  • Nosocomial infection
  • Sepsis

ASJC Scopus subject areas

  • Pediatrics

Cite this

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