Head and neck muscle spasm after radiotherapy

Management with botulinum toxin A injection

Douglas J. Van Daele, Eileen M. Finnegan, Robert L. Rodnitzky, Weining Zhen, Timothy M. McCulloch, Henry T. Hoffman

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Objective: To introduce the concept of neck muscle pain and spasm after radiotherapy and its treatment with botulinum toxin A. Design: Case series. Setting: Ambulatory patients at a tertiary care medical center. Patients: Individuals who had undergone primary or adjuvant radiotherapy for treatment of carcinoma of the head and neck were asked about painful spasms of the neck musculature. A volunteer sample was used. If they desired treatment with botulinum toxin A, they were included in the study, Intervention: Patients received botulinum toxin A injections to the affected sternocleidomastoid muscle(s) in 1 or 2 locations. Outcome Measure: Subjective pain relief. Results: Four of 6 patients with painful tightness of the neck who received botulinum toxin A injections to the sternocleidomastoid muscle achieved pain relief. Conclusions: A subset of patients with irradiation-induced cervical muscle spasm benefit from treatment with botulinum toxin A injections. Further study is needed to more clearly define the entity and treatment.

Original languageEnglish (US)
Pages (from-to)956-959
Number of pages4
JournalArchives of Otolaryngology - Head and Neck Surgery
Volume128
Issue number8
DOIs
StatePublished - Jan 1 2002

Fingerprint

Neck Muscles
Type A Botulinum Toxins
Spasm
Radiotherapy
Head
Injections
Neck
Myalgia
Therapeutics
Adjuvant Radiotherapy
Neck Pain
Tertiary Care Centers
Volunteers
Outcome Assessment (Health Care)
Carcinoma
Pain
Muscles

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

Cite this

Head and neck muscle spasm after radiotherapy : Management with botulinum toxin A injection. / Van Daele, Douglas J.; Finnegan, Eileen M.; Rodnitzky, Robert L.; Zhen, Weining; McCulloch, Timothy M.; Hoffman, Henry T.

In: Archives of Otolaryngology - Head and Neck Surgery, Vol. 128, No. 8, 01.01.2002, p. 956-959.

Research output: Contribution to journalArticle

Van Daele, Douglas J. ; Finnegan, Eileen M. ; Rodnitzky, Robert L. ; Zhen, Weining ; McCulloch, Timothy M. ; Hoffman, Henry T. / Head and neck muscle spasm after radiotherapy : Management with botulinum toxin A injection. In: Archives of Otolaryngology - Head and Neck Surgery. 2002 ; Vol. 128, No. 8. pp. 956-959.
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