Hantavirus pulmonary syndrome in Florida: Association with the newly identified Black Creek Canal virus

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Abstract

Hantavirus pulmonary syndrome (HPS) is a recently recognized vital zoonosis. The first recognized cases were caused by a newly described hantavirus, Sin Nombre virus (previously known as Muerto Canyon virus), isolated from Peromyscus maniculatus (deer mouse). We describe a 33-year-old Floridian man who resided outside the ecologic range of P maniculatus but was found to have serologic evidence of a hantavirus infection during evaluation of azotemia associated with adult respiratory distress syndrome. Small mammal trapping conducted around this patient's residence demonstrated the presence of antihantaviral antibodies in 13% of Sigmodon hispidus (cotton rat). Serologic testing using antigen derived from the Black Creek Canal hantavirus subsequently isolated from this rodent established that this patient was acutely infected with this new pathogenic American hantavirus. HPS is not confined to the geographical distribution of P maniculatus and should be suspected in individuals with febrile respiratory syndromes, perhaps associated with azotemia, throughout the continental United States.

Original languageEnglish (US)
Pages (from-to)46-48
Number of pages3
JournalAmerican Journal of Medicine
Volume100
Issue number1
DOIs
StatePublished - Jan 1 1996

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Hantavirus Pulmonary Syndrome
Hantavirus
Sin Nombre virus
Sigmodontinae
Peromyscus
Azotemia
Viruses
Hantavirus Infections
Adult Respiratory Distress Syndrome
Zoonoses
Mammals
Rodentia
Fever
Antigens
Antibodies

ASJC Scopus subject areas

  • Medicine(all)

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Hantavirus pulmonary syndrome in Florida : Association with the newly identified Black Creek Canal virus. / Khan, Ali S.

In: American Journal of Medicine, Vol. 100, No. 1, 01.01.1996, p. 46-48.

Research output: Contribution to journalArticle

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