Graft polymerization of anti-fouling PEO surfaces by liquid-free initiated chemical vapor deposition

Ranjita K. Bose, Siamak Nejati, David R. Stufflet, Kenneth K.S. Lau

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Poly(ethylene oxide) (PEO), a biomedically important polymer, has been synthesized using a novel liquid-free initiated chemical vapor deposition (iCVD) via a ring-opening cationic polymerization mechanism. In addition, a grafting scheme was used to graft polymerize PEO onto amine-terminated surfaces. FTIR, NMR, and XPS showed a stoichiometric match to linear PEO homopolymer. In addition, XPS confirmed the graft polymerization of PEO to amine anchors on silicon with a high graft density. XPS and GPC were used to measure independently the grafted polymer molecular weight that also showed a narrow weight distribution. The grafted iCVD PEO surfaces were effective in minimizing nonspecific protein adsorption using a fluorescently labeled bovine serum albumin assay.

Original languageEnglish (US)
Pages (from-to)6915-6922
Number of pages8
JournalMacromolecules
Volume45
Issue number17
DOIs
StatePublished - Sep 11 2012

Fingerprint

Polyethylene oxides
Fouling
Grafts
Chemical vapor deposition
Polymerization
Liquids
X ray photoelectron spectroscopy
Amines
Polymers
Cationic polymerization
Ring opening polymerization
Silicon
Bovine Serum Albumin
Homopolymerization
Anchors
Assays
Molecular weight
Nuclear magnetic resonance
Proteins
Adsorption

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Inorganic Chemistry
  • Materials Chemistry

Cite this

Graft polymerization of anti-fouling PEO surfaces by liquid-free initiated chemical vapor deposition. / Bose, Ranjita K.; Nejati, Siamak; Stufflet, David R.; Lau, Kenneth K.S.

In: Macromolecules, Vol. 45, No. 17, 11.09.2012, p. 6915-6922.

Research output: Contribution to journalArticle

Bose, Ranjita K. ; Nejati, Siamak ; Stufflet, David R. ; Lau, Kenneth K.S. / Graft polymerization of anti-fouling PEO surfaces by liquid-free initiated chemical vapor deposition. In: Macromolecules. 2012 ; Vol. 45, No. 17. pp. 6915-6922.
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