Glycogen resynthesis and exercise performance with the addition of fenugreek extract (4-hydroxyisoleucine) to post-exercise carbohydrate feeding

D. Slivka, J. Cuddy, W. Hailes, S. Harger, B. Ruby

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The purpose of this study was to determine the effect of adding fenugreek extract (FG) to post-exercise carbohydrate feeding on glycogen resynthesis and subsequent exercise performance in normoglycemic male endurance athletes. A muscle biopsy sample was obtained from the vastus lateralis from subjects prior to exercise for 5 h at 50% of peak cycling power (52.1 ± 3.3% of VO 2 peak). A second muscle biopsy sample was obtained immediately after exercise. Immediately after and 2 h after the second biopsy subjects ingested either an oral dose of dextrose (GLU) (1.8 g·kg BW-1) or GLU with FG containing 1.99 ± 0.20 mg·kg-1 4-hydroxyisoleucine (GLU + FG) in a randomized, cross-over, double blind design. At 4 h post-exercise a third biopsy was taken and subjects received a standardised meal along with FG or a placebo capsule. At 15 h post-exercise subjects underwent their final muscle biopsy before completing a simulated 40 km cycling time trial. There was no difference in muscle glycogen at any time between GLU and GLU + FG. Additionally, 40 km time trial performance was similar for average power output (221 ± 28 vs. 213 ± 16 watts) and for time to completion (69.7 ± 3.7 vs. 70.5 ± 2.2 min) for the GLU and GLU + FG, respectively. Despite earlier data to the contrary, the present results do not support an effect of fenugreek supplementation on glycogen resynthesis, even though this may have been the result of differences in experimental protocol.

Original languageEnglish (US)
Pages (from-to)439-444
Number of pages6
JournalAmino Acids
Volume35
Issue number2
DOIs
StatePublished - Aug 1 2008

Fingerprint

Trigonella
Biopsy
Glycogen
Carbohydrates
Exercise
Muscle
Muscles
Capsules
Durability
Quadriceps Muscle
4-hydroxyisoleucine
Athletes
Glucose
Meals
Placebos

Keywords

  • 4-Hydroxyisoleucine
  • Exercise
  • Fenugreek
  • Glycogen
  • Trigonella foenum-graecum

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Organic Chemistry

Cite this

Glycogen resynthesis and exercise performance with the addition of fenugreek extract (4-hydroxyisoleucine) to post-exercise carbohydrate feeding. / Slivka, D.; Cuddy, J.; Hailes, W.; Harger, S.; Ruby, B.

In: Amino Acids, Vol. 35, No. 2, 01.08.2008, p. 439-444.

Research output: Contribution to journalArticle

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