Gingival crevicular fluid IL-8: correlation with local IL-1 beta levels and patient estrogen status.

Jeffrey B Payne, Richard A Reinhardt, M. P. Masada, L. M. DuBois, A. C. Allison

Research output: Contribution to journalArticle

55 Scopus citations


Gingival crevicular fluid (GCF) IL-8 and IL-1 beta levels were determined by sandwich enzyme-linked immunosorbent assays. Associations between IL-8 and IL-1 beta GCF levels, and between these cytokines and patient estrogen status were evaluated. IL-8 and IL-1 beta were detected more frequently and in higher amounts/30 s GCF sample in estrogen-deficient patients than in estrogen-sufficient patients. IL-8 and IL-1 beta GCF levels were significantly correlated. These findings suggest that GCF IL-8 levels are associated with patient estrogen status and local IL-1 beta concentrations.

Original languageEnglish (US)
Pages (from-to)451-453
Number of pages3
JournalJournal of Periodontal Research
Issue number6 Pt 1
StatePublished - Nov 1 1993


ASJC Scopus subject areas

  • Periodontics

Cite this