Genetics of coxsackievirus B3 cardiovirulence

S. Tracy, Z. Tu, N. Chapman, G. Hufnagel

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The human enteroviruses, especially the coxsackie B viruses, have been established as aetiologic agents of human inflammatory heart disease, a condition which may lead to dilated cardiomyopathy and heart failure. It is clear from murine models of coxsackievirus B3-induced inflammatory heart disease that not all strains of the virus are cardiovirulent (able to cause disease). Here, we present preliminary data mapping the site in a coxsackievirus B3 genome which determines a cardiovirulent phenotype.

Original languageEnglish (US)
Pages (from-to)15-17
Number of pages3
JournalEuropean Heart Journal
Volume16
Issue numberSUPPL. O
StatePublished - Jan 1 1995

Fingerprint

Enterovirus
Heart Diseases
Human Enterovirus B
Dilated Cardiomyopathy
Heart Failure
Genome
Viruses
Phenotype

Keywords

  • Coxsackievirus B3
  • Enterovirus
  • Inflammatory heart disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Tracy, S., Tu, Z., Chapman, N., & Hufnagel, G. (1995). Genetics of coxsackievirus B3 cardiovirulence. European Heart Journal, 16(SUPPL. O), 15-17.

Genetics of coxsackievirus B3 cardiovirulence. / Tracy, S.; Tu, Z.; Chapman, N.; Hufnagel, G.

In: European Heart Journal, Vol. 16, No. SUPPL. O, 01.01.1995, p. 15-17.

Research output: Contribution to journalArticle

Tracy, S, Tu, Z, Chapman, N & Hufnagel, G 1995, 'Genetics of coxsackievirus B3 cardiovirulence', European Heart Journal, vol. 16, no. SUPPL. O, pp. 15-17.
Tracy S, Tu Z, Chapman N, Hufnagel G. Genetics of coxsackievirus B3 cardiovirulence. European Heart Journal. 1995 Jan 1;16(SUPPL. O):15-17.
Tracy, S. ; Tu, Z. ; Chapman, N. ; Hufnagel, G. / Genetics of coxsackievirus B3 cardiovirulence. In: European Heart Journal. 1995 ; Vol. 16, No. SUPPL. O. pp. 15-17.
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