Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines

Samir Gupta, Dawn Provenzale, Xavier Llor, Amy L. Halverson, William Grady, Daniel C. Chung, Sigurdis Haraldsdottir, Arnold J. Markowitz, Thomas P. Slavin, Heather Hampel, Reid M. Ness, Jennifer M. Weiss, Dennis J. Ahnen, Lee May Chen, Gregory Cooper, Dayna S. Early, Francis M. Giardiello, Michael J. Hall, Stanley R. Hamilton, Priyanka KanthJason B. Klapman, Audrey J. Lazenby, Patrick M. Lynch, Robert J. Mayer, June Mikkelson, Shajan Peter, Scott E. Regenbogen, Mary A. Dwyer, Ndiya Ogba

Research output: Contribution to journalArticle

Abstract

Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

Original languageEnglish (US)
Pages (from-to)1032-1041
Number of pages10
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume17
Issue number9
DOIs
StatePublished - Jan 1 2019

Fingerprint

Colorectal Neoplasms
Hereditary Neoplastic Syndromes
Guidelines
Hereditary Nonpolyposis Colorectal Neoplasms
Risk Reduction Behavior
Heterozygote
Neoplasms

ASJC Scopus subject areas

  • Oncology

Cite this

Genetic/Familial high-risk assessment : Colorectal, version 2.2019 featured updates to the NCCN guidelines. / Gupta, Samir; Provenzale, Dawn; Llor, Xavier; Halverson, Amy L.; Grady, William; Chung, Daniel C.; Haraldsdottir, Sigurdis; Markowitz, Arnold J.; Slavin, Thomas P.; Hampel, Heather; Ness, Reid M.; Weiss, Jennifer M.; Ahnen, Dennis J.; Chen, Lee May; Cooper, Gregory; Early, Dayna S.; Giardiello, Francis M.; Hall, Michael J.; Hamilton, Stanley R.; Kanth, Priyanka; Klapman, Jason B.; Lazenby, Audrey J.; Lynch, Patrick M.; Mayer, Robert J.; Mikkelson, June; Peter, Shajan; Regenbogen, Scott E.; Dwyer, Mary A.; Ogba, Ndiya.

In: JNCCN Journal of the National Comprehensive Cancer Network, Vol. 17, No. 9, 01.01.2019, p. 1032-1041.

Research output: Contribution to journalArticle

Gupta, S, Provenzale, D, Llor, X, Halverson, AL, Grady, W, Chung, DC, Haraldsdottir, S, Markowitz, AJ, Slavin, TP, Hampel, H, Ness, RM, Weiss, JM, Ahnen, DJ, Chen, LM, Cooper, G, Early, DS, Giardiello, FM, Hall, MJ, Hamilton, SR, Kanth, P, Klapman, JB, Lazenby, AJ, Lynch, PM, Mayer, RJ, Mikkelson, J, Peter, S, Regenbogen, SE, Dwyer, MA & Ogba, N 2019, 'Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines', JNCCN Journal of the National Comprehensive Cancer Network, vol. 17, no. 9, pp. 1032-1041. https://doi.org/10.6004/jnccn.2019.0044
Gupta, Samir ; Provenzale, Dawn ; Llor, Xavier ; Halverson, Amy L. ; Grady, William ; Chung, Daniel C. ; Haraldsdottir, Sigurdis ; Markowitz, Arnold J. ; Slavin, Thomas P. ; Hampel, Heather ; Ness, Reid M. ; Weiss, Jennifer M. ; Ahnen, Dennis J. ; Chen, Lee May ; Cooper, Gregory ; Early, Dayna S. ; Giardiello, Francis M. ; Hall, Michael J. ; Hamilton, Stanley R. ; Kanth, Priyanka ; Klapman, Jason B. ; Lazenby, Audrey J. ; Lynch, Patrick M. ; Mayer, Robert J. ; Mikkelson, June ; Peter, Shajan ; Regenbogen, Scott E. ; Dwyer, Mary A. ; Ogba, Ndiya. / Genetic/Familial high-risk assessment : Colorectal, version 2.2019 featured updates to the NCCN guidelines. In: JNCCN Journal of the National Comprehensive Cancer Network. 2019 ; Vol. 17, No. 9. pp. 1032-1041.
@article{8370b1833e4045bba1a7fde5e5463cf7,
title = "Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines",
abstract = "Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.",
author = "Samir Gupta and Dawn Provenzale and Xavier Llor and Halverson, {Amy L.} and William Grady and Chung, {Daniel C.} and Sigurdis Haraldsdottir and Markowitz, {Arnold J.} and Slavin, {Thomas P.} and Heather Hampel and Ness, {Reid M.} and Weiss, {Jennifer M.} and Ahnen, {Dennis J.} and Chen, {Lee May} and Gregory Cooper and Early, {Dayna S.} and Giardiello, {Francis M.} and Hall, {Michael J.} and Hamilton, {Stanley R.} and Priyanka Kanth and Klapman, {Jason B.} and Lazenby, {Audrey J.} and Lynch, {Patrick M.} and Mayer, {Robert J.} and June Mikkelson and Shajan Peter and Regenbogen, {Scott E.} and Dwyer, {Mary A.} and Ndiya Ogba",
year = "2019",
month = "1",
day = "1",
doi = "10.6004/jnccn.2019.0044",
language = "English (US)",
volume = "17",
pages = "1032--1041",
journal = "JNCCN Journal of the National Comprehensive Cancer Network",
issn = "1540-1405",
publisher = "Cold Spring Publishing LLC",
number = "9",

}

TY - JOUR

T1 - Genetic/Familial high-risk assessment

T2 - Colorectal, version 2.2019 featured updates to the NCCN guidelines

AU - Gupta, Samir

AU - Provenzale, Dawn

AU - Llor, Xavier

AU - Halverson, Amy L.

AU - Grady, William

AU - Chung, Daniel C.

AU - Haraldsdottir, Sigurdis

AU - Markowitz, Arnold J.

AU - Slavin, Thomas P.

AU - Hampel, Heather

AU - Ness, Reid M.

AU - Weiss, Jennifer M.

AU - Ahnen, Dennis J.

AU - Chen, Lee May

AU - Cooper, Gregory

AU - Early, Dayna S.

AU - Giardiello, Francis M.

AU - Hall, Michael J.

AU - Hamilton, Stanley R.

AU - Kanth, Priyanka

AU - Klapman, Jason B.

AU - Lazenby, Audrey J.

AU - Lynch, Patrick M.

AU - Mayer, Robert J.

AU - Mikkelson, June

AU - Peter, Shajan

AU - Regenbogen, Scott E.

AU - Dwyer, Mary A.

AU - Ogba, Ndiya

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

AB - Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

UR - http://www.scopus.com/inward/record.url?scp=85071737330&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071737330&partnerID=8YFLogxK

U2 - 10.6004/jnccn.2019.0044

DO - 10.6004/jnccn.2019.0044

M3 - Article

C2 - 31487681

AN - SCOPUS:85071737330

VL - 17

SP - 1032

EP - 1041

JO - JNCCN Journal of the National Comprehensive Cancer Network

JF - JNCCN Journal of the National Comprehensive Cancer Network

SN - 1540-1405

IS - 9

ER -