Genetic interactions underlying hybrid male sterility in the Drosophila bipectinata species complex

Paras Kumar Mishra, Bashisth Narayan Singh

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Understanding genetic mechanisms underlying hybrid male sterility is one of the most challenging problems in evolutionary biology especially speciation. By using the interspecific hybridization method roles of Y chromosome, Major Hybrid Sterility (MHS) genes and cytoplasm in sterility of hybrid males have been investigated in a promising group, the Drosophila bipectinata species complex that consists of four closely related species: D. pseudoananassae, D. bipectinata, D. parabipectinata and D. malerkotliana. The interspecific introgression analyses show that neither cytoplasm nor MHS genes are involved but X-Y interactions may be playing major role in hybrid male sterility between D. pseudoananassae and the other three species. The results of interspecific introgression analyses also show considerable decrease in the number of males in the backcross offspring and all males have atrophied testes. There is a significant positive correlation between sex - ratio distortion and severity of sterility in backcross males. These findings provide evidence that D. pseudoananassae is remotely related with other three species of the D. bipectinata species complex.

Original languageEnglish (US)
Pages (from-to)193-200
Number of pages8
JournalGenes and Genetic Systems
Volume81
Issue number3
DOIs
StatePublished - Aug 21 2006

Fingerprint

Male Infertility
male fertility
Drosophila
Genes
Infertility
Chromosomes
Cytoplasm
introgression
cytoplasm
Y Chromosome
Sex Ratio
interspecific hybridization
Testis
Y chromosome
testes
sex ratio
genes
Biological Sciences

Keywords

  • D. bipectinata species complex
  • Genetic interactions
  • Hybrid male sterility

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Cite this

Genetic interactions underlying hybrid male sterility in the Drosophila bipectinata species complex. / Mishra, Paras Kumar; Singh, Bashisth Narayan.

In: Genes and Genetic Systems, Vol. 81, No. 3, 21.08.2006, p. 193-200.

Research output: Contribution to journalArticle

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