Genetic counseling and clinical management of newly diagnosed breast cancer patients at genetic risk for BRCA germline mutations

Perspective of a surgical oncologist

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Women with a family history of breast cancer who are diagnosed with breast cancer are often counseled to undergo prophylactic mastectomy as part of their treatment for breast cancer. The majority of such individuals make these decisions in haste and without appropriate genetic counseling or testing. Most of them when tested for BRCA or other established mutations find that they are not mutation carriers. In retrospect, this realization leads many to question the wisdom of their prophylactic surgery which is often associated with complications and quality of life problems which they never envisioned. We have designed an algorithm for the management of these patients which minimizes these lifelong problems.

Original languageEnglish (US)
Pages (from-to)91-95
Number of pages5
JournalFamilial Cancer
Volume7
Issue number1
DOIs
StatePublished - Dec 1 2008

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Germ-Line Mutation
Genetic Counseling
Breast Neoplasms
Mutation
Genetic Testing
Quality of Life
Oncologists
Therapeutics

Keywords

  • Breast cancer
  • Clinical management
  • Genetic counseling
  • High risk breast cancer pedigree

ASJC Scopus subject areas

  • Oncology
  • Genetics
  • Genetics(clinical)
  • Cancer Research

Cite this

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