Estudio de 25 años de cáncer del aparato digestivo en cuatro instituciones de la Ciudad de México.

Translated title of the contribution: Gastrointestinal cancer in four medical centers in Mexico City. A 25-year study

J. Jesús Villalobos Pérez, Marco A.Olivera Martínez, Aurora Loaeza del Castillo, M. Luisa Villalobos, Gonzalo M.Torres Villalobos

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10 Scopus citations

Abstract

BACKGROUND: Digestive cancer is an important mortality cause in Mexico. In the past decades a change in the frequency of digestive malignancies has been observed. AIM: To evaluate the frequency of digestive malignancies in four hospitals in México City during a 25 years period. PATIENTS AND METHODS: All digestive cancers were studied at the following hospitals: Hospital General de México (HGM), Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirdn (INCMNSZ), Centro Médico Nacional 20 de Noviembre (CMN20Nov) and Hospital Español (HE). The diagnosis was established by histopathology study. Cases frequency is were compared in three-years intervals. RESULTS: 8,879 digestive cancers were documented. Gastric cancer frequency decreased during the study period at HGM (59% in 1978 to 38% in 2003) and at INCMNSZ (32% in 1978 to 24% in 2003), p = 0.013 andp = 0.012 respectively. Colon cancer frequency increased significantly at HGM (15% in 1978 to 36% in 2003, p < 0.001) and at CMN20Nov (20% in 1981 to 51% in 2003, p < 0.01) and at INCMNSZ with tower significancy. A change in squamous esophageal cancer (SC) and esophageal adenocarcinoma (EA) frequencies was observed in at the INCMNSZ, with a SC:EA ratio of 7:1 between 1977 to 1987and 1:2 between 1988 to 2005. Alimentary habits questionnaries showed early during the study diferences in caloric intake between the four hospitals (mean HGM: 2,169 kcal, INCMNSZ: 2,195 kcal, CMN2O0Nov: 3,133 y 2,262 kcal HE) and in animal protein intake, being lower at HGM (9.3 g/day) and IN-CMNSZ (11.8 g/day) compared with CMN2ONov (45.6 g/day) and HE (63.4 g/day), in the next questionnary these differences dissapeared and there was an increase in both, the same was observed for lipid intake. CONCLUSIONS: We observed a reduction in gastric cancer fre quency and an increase in colon cancer in 25 years, probably associated to a change in habits dietary. Also a change in the main histological type of esophageal cancer was observed, initially epidermoid cancer was the most frequent and in the last 10 years adenocarcinoma is the most frequent.

Original languageSpanish
Pages (from-to)460-472
Number of pages13
JournalRevista de gastroenterología de México
Volume71
Issue number4
Publication statusPublished - Jan 1 2006

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ASJC Scopus subject areas

  • Gastroenterology

Cite this

Pérez, J. J. V., Martínez, M. A. O., del Castillo, A. L., Villalobos, M. L., & Villalobos, G. M. T. (2006). Estudio de 25 años de cáncer del aparato digestivo en cuatro instituciones de la Ciudad de México. Revista de gastroenterología de México, 71(4), 460-472.