Gait characteristics, symptoms, and function in persons with hip osteoarthritis: A longitudinal study with 6 to 7 years of follow-up

Ingrid Eitzen, Linda Fernandes, Heidi Kalleru, Lars Nordsletten, Brian Knarr, May Arna Risberg

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

STUDY DESIGN: Longitudinal laboratory study. OBJECTIVES: (1) To compare gait characteristics between individuals with early-stage hip osteoarthritis who underwent total hip replacement (THR) and those who did not undergo THR, and (2) to evaluate whether gait characteristics, function, and symptoms declined among individuals who did not undergo THR during a 6- to 7-year follow-up. BACKGROUND: The natural history of symptoms, function, and gait changes secondary to hip osteoarthritis, including potential differences at an early stage of disease, is unknown. METHODS: Forty-three individuals (mean age, 58.9 years) with radiographic and symptomatic hip osteoarthritis participated. Outcome measures included 3-D gait analysis; self-reported pain, stiffness, and function; hip range of motion; and the six-minute walk test. Baseline comparisons between individuals who later underwent THR and those who did not undergo THR were made using independent t tests or Mann-Whitney U tests. Comparisons of baseline measures and 6- to 7-year follow-up for the nonoperated individuals were conducted with paired-samples t tests or Wilcoxon signed-rank tests (P<.05). RESULTS: Twelve (27.9%) of the 43 individuals initially evaluated had not undergone THR at the 6- to 7-year follow-up. At baseline, these individuals had larger sagittal plane hip and knee joint excursions, larger joint space width, lower body mass index, and superior self-reported function compared with the individuals who later underwent THR. At the 6- to 7-year follow-up, the individuals who did not undergo THR exhibited no decline in gait characteristics, minimum joint space, or overall function. Furthermore, their self-reported pain had significantly decreased (P = .024). CONCLUSION: Individuals who did not undergo THR during a 6- to 7-year follow-up period did not exhibit a decline in gait, function, or symptoms compared to those who underwent THR. These findings are suggestive of a phenotype of hip osteoarthritis with a very slow disease progression, particularly in regard to pain.

Original languageEnglish (US)
Pages (from-to)539-549
Number of pages11
JournalJournal of Orthopaedic and Sports Physical Therapy
Volume45
Issue number7
DOIs
StatePublished - Jul 1 2015

Fingerprint

Hip Osteoarthritis
Hip Replacement Arthroplasties
Gait
Longitudinal Studies
Nonparametric Statistics
Pain
Joints
Hip Joint
Knee Joint
Articular Range of Motion
Natural History
Disease Progression
Hip
Body Mass Index
Outcome Assessment (Health Care)
Phenotype

Keywords

  • Biomechanics
  • Joint deterioration
  • Motion analysis
  • Nonoperative natural history

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Medicine(all)

Cite this

Gait characteristics, symptoms, and function in persons with hip osteoarthritis : A longitudinal study with 6 to 7 years of follow-up. / Eitzen, Ingrid; Fernandes, Linda; Kalleru, Heidi; Nordsletten, Lars; Knarr, Brian; Risberg, May Arna.

In: Journal of Orthopaedic and Sports Physical Therapy, Vol. 45, No. 7, 01.07.2015, p. 539-549.

Research output: Contribution to journalArticle

Eitzen, Ingrid ; Fernandes, Linda ; Kalleru, Heidi ; Nordsletten, Lars ; Knarr, Brian ; Risberg, May Arna. / Gait characteristics, symptoms, and function in persons with hip osteoarthritis : A longitudinal study with 6 to 7 years of follow-up. In: Journal of Orthopaedic and Sports Physical Therapy. 2015 ; Vol. 45, No. 7. pp. 539-549.
@article{e888dcf5073d40e094469c6c9e5bd557,
title = "Gait characteristics, symptoms, and function in persons with hip osteoarthritis: A longitudinal study with 6 to 7 years of follow-up",
abstract = "STUDY DESIGN: Longitudinal laboratory study. OBJECTIVES: (1) To compare gait characteristics between individuals with early-stage hip osteoarthritis who underwent total hip replacement (THR) and those who did not undergo THR, and (2) to evaluate whether gait characteristics, function, and symptoms declined among individuals who did not undergo THR during a 6- to 7-year follow-up. BACKGROUND: The natural history of symptoms, function, and gait changes secondary to hip osteoarthritis, including potential differences at an early stage of disease, is unknown. METHODS: Forty-three individuals (mean age, 58.9 years) with radiographic and symptomatic hip osteoarthritis participated. Outcome measures included 3-D gait analysis; self-reported pain, stiffness, and function; hip range of motion; and the six-minute walk test. Baseline comparisons between individuals who later underwent THR and those who did not undergo THR were made using independent t tests or Mann-Whitney U tests. Comparisons of baseline measures and 6- to 7-year follow-up for the nonoperated individuals were conducted with paired-samples t tests or Wilcoxon signed-rank tests (P<.05). RESULTS: Twelve (27.9{\%}) of the 43 individuals initially evaluated had not undergone THR at the 6- to 7-year follow-up. At baseline, these individuals had larger sagittal plane hip and knee joint excursions, larger joint space width, lower body mass index, and superior self-reported function compared with the individuals who later underwent THR. At the 6- to 7-year follow-up, the individuals who did not undergo THR exhibited no decline in gait characteristics, minimum joint space, or overall function. Furthermore, their self-reported pain had significantly decreased (P = .024). CONCLUSION: Individuals who did not undergo THR during a 6- to 7-year follow-up period did not exhibit a decline in gait, function, or symptoms compared to those who underwent THR. These findings are suggestive of a phenotype of hip osteoarthritis with a very slow disease progression, particularly in regard to pain.",
keywords = "Biomechanics, Joint deterioration, Motion analysis, Nonoperative natural history",
author = "Ingrid Eitzen and Linda Fernandes and Heidi Kalleru and Lars Nordsletten and Brian Knarr and Risberg, {May Arna}",
year = "2015",
month = "7",
day = "1",
doi = "10.2519/jospt.2015.5441",
language = "English (US)",
volume = "45",
pages = "539--549",
journal = "Journal of Orthopaedic and Sports Physical Therapy",
issn = "0190-6011",
publisher = "JOSPT",
number = "7",

}

TY - JOUR

T1 - Gait characteristics, symptoms, and function in persons with hip osteoarthritis

T2 - A longitudinal study with 6 to 7 years of follow-up

AU - Eitzen, Ingrid

AU - Fernandes, Linda

AU - Kalleru, Heidi

AU - Nordsletten, Lars

AU - Knarr, Brian

AU - Risberg, May Arna

PY - 2015/7/1

Y1 - 2015/7/1

N2 - STUDY DESIGN: Longitudinal laboratory study. OBJECTIVES: (1) To compare gait characteristics between individuals with early-stage hip osteoarthritis who underwent total hip replacement (THR) and those who did not undergo THR, and (2) to evaluate whether gait characteristics, function, and symptoms declined among individuals who did not undergo THR during a 6- to 7-year follow-up. BACKGROUND: The natural history of symptoms, function, and gait changes secondary to hip osteoarthritis, including potential differences at an early stage of disease, is unknown. METHODS: Forty-three individuals (mean age, 58.9 years) with radiographic and symptomatic hip osteoarthritis participated. Outcome measures included 3-D gait analysis; self-reported pain, stiffness, and function; hip range of motion; and the six-minute walk test. Baseline comparisons between individuals who later underwent THR and those who did not undergo THR were made using independent t tests or Mann-Whitney U tests. Comparisons of baseline measures and 6- to 7-year follow-up for the nonoperated individuals were conducted with paired-samples t tests or Wilcoxon signed-rank tests (P<.05). RESULTS: Twelve (27.9%) of the 43 individuals initially evaluated had not undergone THR at the 6- to 7-year follow-up. At baseline, these individuals had larger sagittal plane hip and knee joint excursions, larger joint space width, lower body mass index, and superior self-reported function compared with the individuals who later underwent THR. At the 6- to 7-year follow-up, the individuals who did not undergo THR exhibited no decline in gait characteristics, minimum joint space, or overall function. Furthermore, their self-reported pain had significantly decreased (P = .024). CONCLUSION: Individuals who did not undergo THR during a 6- to 7-year follow-up period did not exhibit a decline in gait, function, or symptoms compared to those who underwent THR. These findings are suggestive of a phenotype of hip osteoarthritis with a very slow disease progression, particularly in regard to pain.

AB - STUDY DESIGN: Longitudinal laboratory study. OBJECTIVES: (1) To compare gait characteristics between individuals with early-stage hip osteoarthritis who underwent total hip replacement (THR) and those who did not undergo THR, and (2) to evaluate whether gait characteristics, function, and symptoms declined among individuals who did not undergo THR during a 6- to 7-year follow-up. BACKGROUND: The natural history of symptoms, function, and gait changes secondary to hip osteoarthritis, including potential differences at an early stage of disease, is unknown. METHODS: Forty-three individuals (mean age, 58.9 years) with radiographic and symptomatic hip osteoarthritis participated. Outcome measures included 3-D gait analysis; self-reported pain, stiffness, and function; hip range of motion; and the six-minute walk test. Baseline comparisons between individuals who later underwent THR and those who did not undergo THR were made using independent t tests or Mann-Whitney U tests. Comparisons of baseline measures and 6- to 7-year follow-up for the nonoperated individuals were conducted with paired-samples t tests or Wilcoxon signed-rank tests (P<.05). RESULTS: Twelve (27.9%) of the 43 individuals initially evaluated had not undergone THR at the 6- to 7-year follow-up. At baseline, these individuals had larger sagittal plane hip and knee joint excursions, larger joint space width, lower body mass index, and superior self-reported function compared with the individuals who later underwent THR. At the 6- to 7-year follow-up, the individuals who did not undergo THR exhibited no decline in gait characteristics, minimum joint space, or overall function. Furthermore, their self-reported pain had significantly decreased (P = .024). CONCLUSION: Individuals who did not undergo THR during a 6- to 7-year follow-up period did not exhibit a decline in gait, function, or symptoms compared to those who underwent THR. These findings are suggestive of a phenotype of hip osteoarthritis with a very slow disease progression, particularly in regard to pain.

KW - Biomechanics

KW - Joint deterioration

KW - Motion analysis

KW - Nonoperative natural history

UR - http://www.scopus.com/inward/record.url?scp=84934284401&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84934284401&partnerID=8YFLogxK

U2 - 10.2519/jospt.2015.5441

DO - 10.2519/jospt.2015.5441

M3 - Article

C2 - 25996360

AN - SCOPUS:84934284401

VL - 45

SP - 539

EP - 549

JO - Journal of Orthopaedic and Sports Physical Therapy

JF - Journal of Orthopaedic and Sports Physical Therapy

SN - 0190-6011

IS - 7

ER -