Fused estimation of sparse connectivity patterns from rest fMRI

Pascal Zille, Vince D. Calhoun, Julia M. Stephen, Tony W Wilson, Yu Ping Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Functional magnetic resonance imaging (fMRI) is a powerful tool to analyze brain development and neuronal activity. Identifying discriminative brain regions between various groups within a population has generated great interest in recent years. In this work, we consider the problem of estimating multiple sparse, co-activated brain regions from fMRI observations belonging to different classes. More precisely, we propose a method to analyze functional connectivity differences between children and young adults. Often, analysis is conducted on each class separately. Here, we propose to rely on a generalized fused Lasso penalty to extract both class-specific and shared co-expressed regions. In order to validate our method, experiments are performed on an fMRI dataset comprised of normally developing children from 8 to 21. The results demonstrate that the proposed method is able to properly extract meaningful sub-networks, which results in improved classification accuracy between the two classes.

Original languageEnglish (US)
Title of host publication2017 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2017 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages6160-6164
Number of pages5
ISBN (Electronic)9781509041176
DOIs
StatePublished - Jun 16 2017
Event2017 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2017 - New Orleans, United States
Duration: Mar 5 2017Mar 9 2017

Publication series

NameICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings
ISSN (Print)1520-6149

Other

Other2017 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2017
CountryUnited States
CityNew Orleans
Period3/5/173/9/17

Fingerprint

Brain
Magnetic Resonance Imaging
Experiments

Keywords

  • Brain Development
  • Classification
  • Joint Lasso
  • Sparse Models

ASJC Scopus subject areas

  • Software
  • Signal Processing
  • Electrical and Electronic Engineering

Cite this

Zille, P., Calhoun, V. D., Stephen, J. M., Wilson, T. W., & Wang, Y. P. (2017). Fused estimation of sparse connectivity patterns from rest fMRI. In 2017 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2017 - Proceedings (pp. 6160-6164). [7953340] (ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICASSP.2017.7953340

Fused estimation of sparse connectivity patterns from rest fMRI. / Zille, Pascal; Calhoun, Vince D.; Stephen, Julia M.; Wilson, Tony W; Wang, Yu Ping.

2017 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2017. p. 6160-6164 7953340 (ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zille, P, Calhoun, VD, Stephen, JM, Wilson, TW & Wang, YP 2017, Fused estimation of sparse connectivity patterns from rest fMRI. in 2017 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2017 - Proceedings., 7953340, ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings, Institute of Electrical and Electronics Engineers Inc., pp. 6160-6164, 2017 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2017, New Orleans, United States, 3/5/17. https://doi.org/10.1109/ICASSP.2017.7953340
Zille P, Calhoun VD, Stephen JM, Wilson TW, Wang YP. Fused estimation of sparse connectivity patterns from rest fMRI. In 2017 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2017. p. 6160-6164. 7953340. (ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings). https://doi.org/10.1109/ICASSP.2017.7953340
Zille, Pascal ; Calhoun, Vince D. ; Stephen, Julia M. ; Wilson, Tony W ; Wang, Yu Ping. / Fused estimation of sparse connectivity patterns from rest fMRI. 2017 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2017. pp. 6160-6164 (ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings).
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