Free tissue transfer and local flap complications in anterior and anterolateral skull base surgery

Jason A. Heth, Gerry F. Funk, Lucy H. Karnell, Timothy M. McCulloch, Vincent C. Traynelis, Jeffrey A. Nerad, Russell B Smith, Scott M. Graham, Henry T. Hoffman

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Background. Advances in reconstructive techniques over the past two decades have allowed the resection of more extensive skull base tumors than had previously been possible. Despite this progress, complications related to these cases remain a concern. Methods. Univariate and multivariate analyses were used to determine the relationship of host, tumor, defect, treatment, and reconstructive variables to wound and systemic complications after anterior and anterolateral skull base resections. The study included 67 patients receiving local flap (LF) or free tissue transfer (FTT) reconstructions during an 8-year period. Results. Overall, 28% of patients had a major wound complication, and 19% had a major systemic complication. LF and FTT flaps had similar rates of wound complications. LF reconstructions were associated with late wound breakdown problems, and FTT flap complications were primarily acute surgery-related problems. Conclusions. The surgical reconstruction of skull base defects should be planned on the basis of the ability of the technique to attain safe closure and maintain integrity after radiation therapy.

Original languageEnglish (US)
Pages (from-to)901-912
Number of pages12
JournalHead and Neck
Volume24
Issue number10
DOIs
StatePublished - Oct 1 2002

Fingerprint

Free Tissue Flaps
Skull Base
Wounds and Injuries
Neoplasms
Radiotherapy
Multivariate Analysis
Therapeutics

Keywords

  • Anterior skull base surgery
  • Free tissue transfer
  • Pericranial flaps
  • Surgical complications

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Heth, J. A., Funk, G. F., Karnell, L. H., McCulloch, T. M., Traynelis, V. C., Nerad, J. A., ... Hoffman, H. T. (2002). Free tissue transfer and local flap complications in anterior and anterolateral skull base surgery. Head and Neck, 24(10), 901-912. https://doi.org/10.1002/hed.10147

Free tissue transfer and local flap complications in anterior and anterolateral skull base surgery. / Heth, Jason A.; Funk, Gerry F.; Karnell, Lucy H.; McCulloch, Timothy M.; Traynelis, Vincent C.; Nerad, Jeffrey A.; Smith, Russell B; Graham, Scott M.; Hoffman, Henry T.

In: Head and Neck, Vol. 24, No. 10, 01.10.2002, p. 901-912.

Research output: Contribution to journalArticle

Heth, JA, Funk, GF, Karnell, LH, McCulloch, TM, Traynelis, VC, Nerad, JA, Smith, RB, Graham, SM & Hoffman, HT 2002, 'Free tissue transfer and local flap complications in anterior and anterolateral skull base surgery', Head and Neck, vol. 24, no. 10, pp. 901-912. https://doi.org/10.1002/hed.10147
Heth JA, Funk GF, Karnell LH, McCulloch TM, Traynelis VC, Nerad JA et al. Free tissue transfer and local flap complications in anterior and anterolateral skull base surgery. Head and Neck. 2002 Oct 1;24(10):901-912. https://doi.org/10.1002/hed.10147
Heth, Jason A. ; Funk, Gerry F. ; Karnell, Lucy H. ; McCulloch, Timothy M. ; Traynelis, Vincent C. ; Nerad, Jeffrey A. ; Smith, Russell B ; Graham, Scott M. ; Hoffman, Henry T. / Free tissue transfer and local flap complications in anterior and anterolateral skull base surgery. In: Head and Neck. 2002 ; Vol. 24, No. 10. pp. 901-912.
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