Fournier's gangrene complicating aggressive therapy for hematologic malignancy

A. Berg, James Olen Armitage, C. P. Burns

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

The authors describe two cases of Fournier's gangrene complicating aggressive therapy for hematologic malignancies. Fournier's gangrene is a fulminant necrotizing fasciitis of the scrotum and penis, often with an infectious etiology. Only one prior case has been reported in a patient receiving aggressive chemotherapy for a hematologic malignancy. Unique to these three cases was profound granulocytopenia and the culturing of Pseudomonas aeruginosa in both the blood and necrotic perineal—scrotal tissue. Maintaining a high index of suspicion with early recognition and aggressive therapy may decrease the morbidity and mortality of this devastating and life‐threatening infection in the compromised host. Cancer 57:2291–2294, 1986.

Original languageEnglish (US)
Pages (from-to)2291-2294
Number of pages4
JournalCancer
Volume57
Issue number12
DOIs
StatePublished - Jan 1 1986

Fingerprint

Fournier Gangrene
Hematologic Neoplasms
Necrotizing Fasciitis
Agranulocytosis
Scrotum
Penis
Pseudomonas aeruginosa
Morbidity
Drug Therapy
Mortality
Therapeutics
Infection
Neoplasms

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Fournier's gangrene complicating aggressive therapy for hematologic malignancy. / Berg, A.; Armitage, James Olen; Burns, C. P.

In: Cancer, Vol. 57, No. 12, 01.01.1986, p. 2291-2294.

Research output: Contribution to journalArticle

Berg, A. ; Armitage, James Olen ; Burns, C. P. / Fournier's gangrene complicating aggressive therapy for hematologic malignancy. In: Cancer. 1986 ; Vol. 57, No. 12. pp. 2291-2294.
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