Food-derived bioactive peptides and their role in ameliorating hypertension and associated cardiovascular diseases

Advaita Ganguly, Kumakshi Sharma, Kaustav Majumder

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Non-communicable diseases including cardiovascular diseases (CVDs) and associated metabolic disorders are responsible for nearly 40 million deaths globally per year. Hypertension or high blood pressure (BP) is one of the primary reasons for the development of CVDs. A healthy nutritional strategy complementing with physical activity can substantially reduce high BP and prevent the occurrence of CVD-associated morbidity and mortality. Bioactive peptides currently are the next wave of the promising bench to clinic options for potential targeting chronic and acute health issues including hypertension. Peptides demonstrating anti-inflammatory, anti-oxidant, and angiotensin-converting enzyme-I inhibitory activity are widely studied for the amelioration of hypertension and associated CVDs. Isolating these potent bioactive peptides from different food sources is a promising endeavor toward nutraceutical based dietary management and prevention of hypertension. Understanding the pathophysiology of hypertension and the action mechanisms of the bioactive peptides would complement in designing and characterizing more potent peptides and suitable comprehensive dietary plans for the prevention of hypertension and associated CVDs.

Original languageEnglish (US)
Title of host publicationAdvances in Food and Nutrition Research
EditorsFidel Toldrá
PublisherAcademic Press Inc.
Pages165-207
Number of pages43
ISBN (Print)9780128171714
DOIs
StatePublished - 2019

Publication series

NameAdvances in Food and Nutrition Research
Volume89
ISSN (Print)1043-4526

Fingerprint

hypertension
cardiovascular diseases
Cardiovascular Diseases
peptides
Hypertension
Food
Peptides
noninfectious diseases
peptidyl-dipeptidase A
metabolic diseases
Peptidyl-Dipeptidase A
Dietary Supplements
pathophysiology
Oxidants
oxidants
physical activity
functional foods
morbidity
mechanism of action
complement

Keywords

  • ACE inhibition
  • Angiotensin-II
  • Anti-inflammation
  • Anti-oxidant
  • Bioactive peptides
  • Cardiovascular diseases
  • Chronic inflammation
  • Hypertension
  • Oxidative stress
  • Peptide therapeutics
  • Renin-angiotensin system
  • Structural information

ASJC Scopus subject areas

  • Food Science

Cite this

Ganguly, A., Sharma, K., & Majumder, K. (2019). Food-derived bioactive peptides and their role in ameliorating hypertension and associated cardiovascular diseases. In F. Toldrá (Ed.), Advances in Food and Nutrition Research (pp. 165-207). (Advances in Food and Nutrition Research; Vol. 89). Academic Press Inc.. https://doi.org/10.1016/bs.afnr.2019.04.001

Food-derived bioactive peptides and their role in ameliorating hypertension and associated cardiovascular diseases. / Ganguly, Advaita; Sharma, Kumakshi; Majumder, Kaustav.

Advances in Food and Nutrition Research. ed. / Fidel Toldrá. Academic Press Inc., 2019. p. 165-207 (Advances in Food and Nutrition Research; Vol. 89).

Research output: Chapter in Book/Report/Conference proceedingChapter

Ganguly, A, Sharma, K & Majumder, K 2019, Food-derived bioactive peptides and their role in ameliorating hypertension and associated cardiovascular diseases. in F Toldrá (ed.), Advances in Food and Nutrition Research. Advances in Food and Nutrition Research, vol. 89, Academic Press Inc., pp. 165-207. https://doi.org/10.1016/bs.afnr.2019.04.001
Ganguly A, Sharma K, Majumder K. Food-derived bioactive peptides and their role in ameliorating hypertension and associated cardiovascular diseases. In Toldrá F, editor, Advances in Food and Nutrition Research. Academic Press Inc. 2019. p. 165-207. (Advances in Food and Nutrition Research). https://doi.org/10.1016/bs.afnr.2019.04.001
Ganguly, Advaita ; Sharma, Kumakshi ; Majumder, Kaustav. / Food-derived bioactive peptides and their role in ameliorating hypertension and associated cardiovascular diseases. Advances in Food and Nutrition Research. editor / Fidel Toldrá. Academic Press Inc., 2019. pp. 165-207 (Advances in Food and Nutrition Research).
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