Fluid-structure interaction in abdominal aortic aneurysm

Effect of modeling techniques

Shengmao Lin, Xinwei Han, Yonghua Bi, Siyeong Ju, Linxia Gu

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

In this work, the impact of modeling techniques on predicting the mechanical behaviors of abdominal aortic aneurysm (AAA) is systematically investigated. The fluid-structure interaction (FSI) model for simultaneously capturing the transient interaction between blood flow dynamics and wall mechanics was compared with its simplified techniques, that is, computational fluid dynamics (CFD) or computational solid stress (CSS) model. Results demonstrated that CFD exhibited relatively smaller vortexes and tends to overestimate the fluid wall shear stress, compared to FSI. On the contrary, the minimal differences in wall stresses and deformation were observed between FSI and CSS models. Furthermore, it was found that the accuracy of CSS prediction depends on the applied pressure profile for the aneurysm sac. A large pressure drop across AAA usually led to the underestimation of wall stresses and thus the AAA rupture. Moreover, the assumed isotropic AAA wall properties, compared to the anisotropic one, will aggravate the difference between the simplified models with the FSI approach. The present work demonstrated the importance of modeling techniques on predicting the blood flow dynamics and wall mechanics of the AAA, which could guide the selection of appropriate modeling technique for significant clinical implications.

Original languageEnglish (US)
Article number7023078
JournalBioMed Research International
Volume2017
DOIs
StatePublished - Jan 1 2017

Fingerprint

Fluid structure interaction
Abdominal Aortic Aneurysm
Hydrodynamics
Mechanics
Computational fluid dynamics
Blood
Pressure
Aortic Rupture
Pressure drop
Aneurysm
Shear stress
Vortex flow
Fluids

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Fluid-structure interaction in abdominal aortic aneurysm : Effect of modeling techniques. / Lin, Shengmao; Han, Xinwei; Bi, Yonghua; Ju, Siyeong; Gu, Linxia.

In: BioMed Research International, Vol. 2017, 7023078, 01.01.2017.

Research output: Contribution to journalArticle

@article{eb830a0a75d048318c070c5af8b3b528,
title = "Fluid-structure interaction in abdominal aortic aneurysm: Effect of modeling techniques",
abstract = "In this work, the impact of modeling techniques on predicting the mechanical behaviors of abdominal aortic aneurysm (AAA) is systematically investigated. The fluid-structure interaction (FSI) model for simultaneously capturing the transient interaction between blood flow dynamics and wall mechanics was compared with its simplified techniques, that is, computational fluid dynamics (CFD) or computational solid stress (CSS) model. Results demonstrated that CFD exhibited relatively smaller vortexes and tends to overestimate the fluid wall shear stress, compared to FSI. On the contrary, the minimal differences in wall stresses and deformation were observed between FSI and CSS models. Furthermore, it was found that the accuracy of CSS prediction depends on the applied pressure profile for the aneurysm sac. A large pressure drop across AAA usually led to the underestimation of wall stresses and thus the AAA rupture. Moreover, the assumed isotropic AAA wall properties, compared to the anisotropic one, will aggravate the difference between the simplified models with the FSI approach. The present work demonstrated the importance of modeling techniques on predicting the blood flow dynamics and wall mechanics of the AAA, which could guide the selection of appropriate modeling technique for significant clinical implications.",
author = "Shengmao Lin and Xinwei Han and Yonghua Bi and Siyeong Ju and Linxia Gu",
year = "2017",
month = "1",
day = "1",
doi = "10.1155/2017/7023078",
language = "English (US)",
volume = "2017",
journal = "BioMed Research International",
issn = "2314-6133",
publisher = "Hindawi Publishing Corporation",

}

TY - JOUR

T1 - Fluid-structure interaction in abdominal aortic aneurysm

T2 - Effect of modeling techniques

AU - Lin, Shengmao

AU - Han, Xinwei

AU - Bi, Yonghua

AU - Ju, Siyeong

AU - Gu, Linxia

PY - 2017/1/1

Y1 - 2017/1/1

N2 - In this work, the impact of modeling techniques on predicting the mechanical behaviors of abdominal aortic aneurysm (AAA) is systematically investigated. The fluid-structure interaction (FSI) model for simultaneously capturing the transient interaction between blood flow dynamics and wall mechanics was compared with its simplified techniques, that is, computational fluid dynamics (CFD) or computational solid stress (CSS) model. Results demonstrated that CFD exhibited relatively smaller vortexes and tends to overestimate the fluid wall shear stress, compared to FSI. On the contrary, the minimal differences in wall stresses and deformation were observed between FSI and CSS models. Furthermore, it was found that the accuracy of CSS prediction depends on the applied pressure profile for the aneurysm sac. A large pressure drop across AAA usually led to the underestimation of wall stresses and thus the AAA rupture. Moreover, the assumed isotropic AAA wall properties, compared to the anisotropic one, will aggravate the difference between the simplified models with the FSI approach. The present work demonstrated the importance of modeling techniques on predicting the blood flow dynamics and wall mechanics of the AAA, which could guide the selection of appropriate modeling technique for significant clinical implications.

AB - In this work, the impact of modeling techniques on predicting the mechanical behaviors of abdominal aortic aneurysm (AAA) is systematically investigated. The fluid-structure interaction (FSI) model for simultaneously capturing the transient interaction between blood flow dynamics and wall mechanics was compared with its simplified techniques, that is, computational fluid dynamics (CFD) or computational solid stress (CSS) model. Results demonstrated that CFD exhibited relatively smaller vortexes and tends to overestimate the fluid wall shear stress, compared to FSI. On the contrary, the minimal differences in wall stresses and deformation were observed between FSI and CSS models. Furthermore, it was found that the accuracy of CSS prediction depends on the applied pressure profile for the aneurysm sac. A large pressure drop across AAA usually led to the underestimation of wall stresses and thus the AAA rupture. Moreover, the assumed isotropic AAA wall properties, compared to the anisotropic one, will aggravate the difference between the simplified models with the FSI approach. The present work demonstrated the importance of modeling techniques on predicting the blood flow dynamics and wall mechanics of the AAA, which could guide the selection of appropriate modeling technique for significant clinical implications.

UR - http://www.scopus.com/inward/record.url?scp=85016035777&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85016035777&partnerID=8YFLogxK

U2 - 10.1155/2017/7023078

DO - 10.1155/2017/7023078

M3 - Article

VL - 2017

JO - BioMed Research International

JF - BioMed Research International

SN - 2314-6133

M1 - 7023078

ER -