Finite element model of the patched human carotid

Alexey Kamenskiy, Iraklis I Pipinos, Anastasia S. Desyatova, Yuriy E. Salkovskiy, Leonid Yu Kossovich, Irina V. Kirillova, Leo A. Bockeria, Konstantin M. Morozov, Vasiliy O. Polyaev, Thomas G. Lynch, Yuris Dzenis

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Introduction: The hemodynamic effects of carotid artery patching are not well known. Our objective was to develop a fluid-solid finite element model of the endarterectomized and patched carotid artery. Methods: Hyperelastic materials parameters were determined from studies of 8 cadaveric carotids. Blood flow characteristics were based on intraoperative data from a patient undergoing endarterectomy. Wall shear stress, cyclic strain and effective stress were computed as hemodynamic parameters with known association with endothelial injury, neointimal hyperplasia abd atherogenesis. Results: Low wall shear stress, high cyclic strain and high effective stress were identified diffusely in the carotid bulb, at the margins around the patch and in the flow divider. Conclusion: Endarterectomy and Polytetrafluoroethylene patching produce considerable abnormalities in the hemodynamics of the repaired carotid. Advanced mechanical modeling can be used to evaluate different carotid revascularization approaches to obtain optimized biomechanical and hemodynamic results for the care of patients with carotid bifurcation disease.

Original languageEnglish (US)
Pages (from-to)533-541
Number of pages9
JournalVascular and Endovascular Surgery
Volume43
Issue number6
DOIs
StatePublished - Dec 1 2009

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Hemodynamics
Endarterectomy
Carotid Arteries
Polytetrafluoroethylene
Hyperplasia
Atherosclerosis
Patient Care
Wounds and Injuries

Keywords

  • Carotid disease
  • Endarterectomy
  • Finite element model
  • Patching

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

Cite this

Finite element model of the patched human carotid. / Kamenskiy, Alexey; Pipinos, Iraklis I; Desyatova, Anastasia S.; Salkovskiy, Yuriy E.; Yu Kossovich, Leonid; Kirillova, Irina V.; Bockeria, Leo A.; Morozov, Konstantin M.; Polyaev, Vasiliy O.; Lynch, Thomas G.; Dzenis, Yuris.

In: Vascular and Endovascular Surgery, Vol. 43, No. 6, 01.12.2009, p. 533-541.

Research output: Contribution to journalArticle

Kamenskiy, A, Pipinos, II, Desyatova, AS, Salkovskiy, YE, Yu Kossovich, L, Kirillova, IV, Bockeria, LA, Morozov, KM, Polyaev, VO, Lynch, TG & Dzenis, Y 2009, 'Finite element model of the patched human carotid', Vascular and Endovascular Surgery, vol. 43, no. 6, pp. 533-541. https://doi.org/10.1177/1538574409345030
Kamenskiy A, Pipinos II, Desyatova AS, Salkovskiy YE, Yu Kossovich L, Kirillova IV et al. Finite element model of the patched human carotid. Vascular and Endovascular Surgery. 2009 Dec 1;43(6):533-541. https://doi.org/10.1177/1538574409345030
Kamenskiy, Alexey ; Pipinos, Iraklis I ; Desyatova, Anastasia S. ; Salkovskiy, Yuriy E. ; Yu Kossovich, Leonid ; Kirillova, Irina V. ; Bockeria, Leo A. ; Morozov, Konstantin M. ; Polyaev, Vasiliy O. ; Lynch, Thomas G. ; Dzenis, Yuris. / Finite element model of the patched human carotid. In: Vascular and Endovascular Surgery. 2009 ; Vol. 43, No. 6. pp. 533-541.
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