Fetal hydronephrosis as a predictor of neonatal urologic outcomes

Alireza A. Shamshirsaz, Samadh F. Ravangard, James F. Egan, Ann Marie Prabulos, Amirhoushang A. Shamshirsaz, Fernando A. Ferrer, John H. Makari, Heidi K. Leftwich, Katherine W. Herbst, Rachel A. Billstrom, Allison Sadowski, Padmalatha Gurram, Winston A. Campbell

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Objectives - The ability to predict surgically relevant fetal renal hydronephrosis is limited. We sought to determine the most efficacious second- and third-trimester fetal renal pelvis anteroposterior diameter cutoffs to predict the need for postnatal surgery. Methods - We retrospectively reviewed the medical records of mothers and neonates who had a prenatal sonographic examination in our Perinatal-Pediatric Urology Clinic and received follow-up care. Hydronephrosis was defined as a renal pelvis anteroposterior diameter of 5 mm or greater in the second trimester and 7 mm or greater in the third trimester. Hydronephrosis was subdivided into mild, moderate, and severe. Results - Of 8453 fetuses, 96 met the criteria and were referred to our clinic. Isolated hydronephrosis was diagnosed in 74 fetuses, of which 53 received postnatal follow-up evaluations. The areas under the receiver operating characteristic curves for predicting postnatal surgery in the second and third trimesters were 0.770 and 0.899, respectively. The second-trimester renal anteroposterior diameter threshold that best predicted postnatal surgery was 9.5 mm (sensitivity, 71.4%; specificity, 81.1%). The third-trimester threshold that best predicted postnatal surgery was 15.0 mm (sensitivity, 85.7%; specificity, 94.6%). Conclusions - The fetal renal anteroposterior diameter on second- and third-trimester sonography is predictive of an increased risk for neonatal urologic surgery. Surgical risk is best predicted by a third-trimester renal anteroposterior diameter threshold of 15 mm.

Original languageEnglish (US)
Pages (from-to)947-954
Number of pages8
JournalJournal of Ultrasound in Medicine
Volume31
Issue number6
DOIs
StatePublished - Jun 1 2012

Fingerprint

Hydronephrosis
Third Pregnancy Trimester
Second Pregnancy Trimester
Kidney
Kidney Pelvis
Fetus
Aftercare
Urology
ROC Curve
Medical Records
Ultrasonography
Pediatrics

Keywords

  • Hydronephrosis
  • Pyelectasis
  • Sonography
  • Surgery

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Shamshirsaz, A. A., Ravangard, S. F., Egan, J. F., Prabulos, A. M., Shamshirsaz, A. A., Ferrer, F. A., ... Campbell, W. A. (2012). Fetal hydronephrosis as a predictor of neonatal urologic outcomes. Journal of Ultrasound in Medicine, 31(6), 947-954. https://doi.org/10.7863/jum.2012.31.6.947

Fetal hydronephrosis as a predictor of neonatal urologic outcomes. / Shamshirsaz, Alireza A.; Ravangard, Samadh F.; Egan, James F.; Prabulos, Ann Marie; Shamshirsaz, Amirhoushang A.; Ferrer, Fernando A.; Makari, John H.; Leftwich, Heidi K.; Herbst, Katherine W.; Billstrom, Rachel A.; Sadowski, Allison; Gurram, Padmalatha; Campbell, Winston A.

In: Journal of Ultrasound in Medicine, Vol. 31, No. 6, 01.06.2012, p. 947-954.

Research output: Contribution to journalArticle

Shamshirsaz, AA, Ravangard, SF, Egan, JF, Prabulos, AM, Shamshirsaz, AA, Ferrer, FA, Makari, JH, Leftwich, HK, Herbst, KW, Billstrom, RA, Sadowski, A, Gurram, P & Campbell, WA 2012, 'Fetal hydronephrosis as a predictor of neonatal urologic outcomes', Journal of Ultrasound in Medicine, vol. 31, no. 6, pp. 947-954. https://doi.org/10.7863/jum.2012.31.6.947
Shamshirsaz AA, Ravangard SF, Egan JF, Prabulos AM, Shamshirsaz AA, Ferrer FA et al. Fetal hydronephrosis as a predictor of neonatal urologic outcomes. Journal of Ultrasound in Medicine. 2012 Jun 1;31(6):947-954. https://doi.org/10.7863/jum.2012.31.6.947
Shamshirsaz, Alireza A. ; Ravangard, Samadh F. ; Egan, James F. ; Prabulos, Ann Marie ; Shamshirsaz, Amirhoushang A. ; Ferrer, Fernando A. ; Makari, John H. ; Leftwich, Heidi K. ; Herbst, Katherine W. ; Billstrom, Rachel A. ; Sadowski, Allison ; Gurram, Padmalatha ; Campbell, Winston A. / Fetal hydronephrosis as a predictor of neonatal urologic outcomes. In: Journal of Ultrasound in Medicine. 2012 ; Vol. 31, No. 6. pp. 947-954.
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abstract = "Objectives - The ability to predict surgically relevant fetal renal hydronephrosis is limited. We sought to determine the most efficacious second- and third-trimester fetal renal pelvis anteroposterior diameter cutoffs to predict the need for postnatal surgery. Methods - We retrospectively reviewed the medical records of mothers and neonates who had a prenatal sonographic examination in our Perinatal-Pediatric Urology Clinic and received follow-up care. Hydronephrosis was defined as a renal pelvis anteroposterior diameter of 5 mm or greater in the second trimester and 7 mm or greater in the third trimester. Hydronephrosis was subdivided into mild, moderate, and severe. Results - Of 8453 fetuses, 96 met the criteria and were referred to our clinic. Isolated hydronephrosis was diagnosed in 74 fetuses, of which 53 received postnatal follow-up evaluations. The areas under the receiver operating characteristic curves for predicting postnatal surgery in the second and third trimesters were 0.770 and 0.899, respectively. The second-trimester renal anteroposterior diameter threshold that best predicted postnatal surgery was 9.5 mm (sensitivity, 71.4{\%}; specificity, 81.1{\%}). The third-trimester threshold that best predicted postnatal surgery was 15.0 mm (sensitivity, 85.7{\%}; specificity, 94.6{\%}). Conclusions - The fetal renal anteroposterior diameter on second- and third-trimester sonography is predictive of an increased risk for neonatal urologic surgery. Surgical risk is best predicted by a third-trimester renal anteroposterior diameter threshold of 15 mm.",
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AU - Shamshirsaz, Amirhoushang A.

AU - Ferrer, Fernando A.

AU - Makari, John H.

AU - Leftwich, Heidi K.

AU - Herbst, Katherine W.

AU - Billstrom, Rachel A.

AU - Sadowski, Allison

AU - Gurram, Padmalatha

AU - Campbell, Winston A.

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N2 - Objectives - The ability to predict surgically relevant fetal renal hydronephrosis is limited. We sought to determine the most efficacious second- and third-trimester fetal renal pelvis anteroposterior diameter cutoffs to predict the need for postnatal surgery. Methods - We retrospectively reviewed the medical records of mothers and neonates who had a prenatal sonographic examination in our Perinatal-Pediatric Urology Clinic and received follow-up care. Hydronephrosis was defined as a renal pelvis anteroposterior diameter of 5 mm or greater in the second trimester and 7 mm or greater in the third trimester. Hydronephrosis was subdivided into mild, moderate, and severe. Results - Of 8453 fetuses, 96 met the criteria and were referred to our clinic. Isolated hydronephrosis was diagnosed in 74 fetuses, of which 53 received postnatal follow-up evaluations. The areas under the receiver operating characteristic curves for predicting postnatal surgery in the second and third trimesters were 0.770 and 0.899, respectively. The second-trimester renal anteroposterior diameter threshold that best predicted postnatal surgery was 9.5 mm (sensitivity, 71.4%; specificity, 81.1%). The third-trimester threshold that best predicted postnatal surgery was 15.0 mm (sensitivity, 85.7%; specificity, 94.6%). Conclusions - The fetal renal anteroposterior diameter on second- and third-trimester sonography is predictive of an increased risk for neonatal urologic surgery. Surgical risk is best predicted by a third-trimester renal anteroposterior diameter threshold of 15 mm.

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KW - Pyelectasis

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