Fetal alcohol spectrum disorders: A population based study of premature mortality rates in the mothers

Qing Li, Wayne W Fisher, Chun Zi Peng, Andrew D. Williams, Larry Burd

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Fetal alcohol spectrum disorders (FASD) are associated with an increase in risk for mortality for people with an FASD and their siblings. In this study we examine mortality rates of birth mothers of children with FASD, using a retrospective case control methodology. We utilized the North Dakota FASD Registry to locate birth certificates for children with FASD which we used to identify birth mothers. We then searched for mothers' death certificates. We then compared the mortality rates of the birth mothers with an age matched control group comprised of all North Dakota women who were born and died in the same year as the birth mother. The birth mothers of children with FASD had a mortality rate of 15/304 = 4.93%; (95% CI 2.44-7.43%). The mortality rate for control mothers born in same years as the FASD mothers was 126/114,714 = 0.11% (95% CI 0.09-0.13%). Mothers of children with an FASD had a 44.82 fold increase in mortality risk and 87% of the deaths occurred in women under the age of 50. Three causes of death (cancer, injuries, and alcohol related disease) accounted for 67% of the deaths in the mothers of children with FASD. A diagnosis of FASD is an important risk marker for premature death in the mothers of children diagnosed with an FASD. These women should be encouraged to enter substance abuse treatment.

Original languageEnglish (US)
Pages (from-to)1332-1337
Number of pages6
JournalMaternal and Child Health Journal
Volume16
Issue number6
DOIs
StatePublished - Aug 1 2012

Fingerprint

Fetal Alcohol Spectrum Disorders
Premature Mortality
Mothers
Mortality
Population
Parturition
Birth Certificates
Death Certificates
Substance-Related Disorders
Registries
Siblings
Cause of Death
Research Design
Alcohols

Keywords

  • Children
  • Etiology
  • Fetal alcohol spectrum disorder
  • Maternal mortality
  • Mother

ASJC Scopus subject areas

  • Epidemiology
  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology
  • Public Health, Environmental and Occupational Health

Cite this

Fetal alcohol spectrum disorders : A population based study of premature mortality rates in the mothers. / Li, Qing; Fisher, Wayne W; Peng, Chun Zi; Williams, Andrew D.; Burd, Larry.

In: Maternal and Child Health Journal, Vol. 16, No. 6, 01.08.2012, p. 1332-1337.

Research output: Contribution to journalArticle

Li, Qing ; Fisher, Wayne W ; Peng, Chun Zi ; Williams, Andrew D. ; Burd, Larry. / Fetal alcohol spectrum disorders : A population based study of premature mortality rates in the mothers. In: Maternal and Child Health Journal. 2012 ; Vol. 16, No. 6. pp. 1332-1337.
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