Feeding patterns of rats chronically ingesting an ethanol-containing liquid diet

Roger D. Reidelberger, Dean J. Tuma, Todd A. Woltman, Terrence Donohue

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

We compared the feeding patterns of rata ingesting a 36% ethanol- containing liquid diet for 30 days with those of rats pair-fed an isocaloric liquid control diet or provided control diet or ground rat chow ad libitum. Ethanol-fed rats consumed fewer calories per day and gained less body weight than rate fed control diets ad libitum. Daily caloric intakes were ~50% lower during the first 10 days and 20% thereafter. Lower intakes in ethanol- fed rats occurred through a decrease in mean meal size rather than number of meals per day, although meals were moro evenly distributed diurnally. Pair- fed rata ingested most of their food in one or two meals within a few hours of presentation. In a related experiment, a 4-hr duodenal infusion of ethanol st a rate comparable to that of ethanol ingestion resulted in plasma ethanol levels of 28 ± 4 mM and suppressed 5-hr intake by ~40% by increasing the mean postmeal interval and satiety ratio. These results suggest that the suppressive effect of ethanol ingestion on food intake may be mediated in part by a post-gastric mechanism of ethanol action.

Original languageEnglish (US)
Pages (from-to)1275-1282
Number of pages8
JournalAlcoholism: Clinical and Experimental Research
Volume20
Issue number7
DOIs
StatePublished - Nov 5 1996

Fingerprint

Feeding Behavior
Nutrition
Rats
Ethanol
Diet
Liquids
Meals
Eating
Energy Intake
Stomach
Body Weight
Plasmas
Food

Keywords

  • Alcohol
  • Blood Alcohol
  • Food Intake
  • Small Intestine

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health

Cite this

Feeding patterns of rats chronically ingesting an ethanol-containing liquid diet. / Reidelberger, Roger D.; Tuma, Dean J.; Woltman, Todd A.; Donohue, Terrence.

In: Alcoholism: Clinical and Experimental Research, Vol. 20, No. 7, 05.11.1996, p. 1275-1282.

Research output: Contribution to journalArticle

Reidelberger, Roger D. ; Tuma, Dean J. ; Woltman, Todd A. ; Donohue, Terrence. / Feeding patterns of rats chronically ingesting an ethanol-containing liquid diet. In: Alcoholism: Clinical and Experimental Research. 1996 ; Vol. 20, No. 7. pp. 1275-1282.
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