Failure of elimination of paternal mitochondrial DNA in abnormal embryos

Justin St John, Denny Sakkas, Konstantina Dimitriadi, Annette Barnes, Victoria Maclin, Jacques Ramey, Christopher Barratt, Christopher De Jonge

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

Paternal mitochondrial DNA is normally eliminated from mammalian embryos. We have shown the presence of paternal mtDNA at the blastocyst stage in some abnormal human embryos.

Original languageEnglish (US)
Number of pages1
JournalLancet
Volume355
Issue number9199
DOIs
StatePublished - Jan 15 2000

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Mitochondrial DNA
Embryonic Structures
Mammalian Embryo
Blastocyst

ASJC Scopus subject areas

  • Medicine(all)

Cite this

St John, J., Sakkas, D., Dimitriadi, K., Barnes, A., Maclin, V., Ramey, J., ... De Jonge, C. (2000). Failure of elimination of paternal mitochondrial DNA in abnormal embryos. Lancet, 355(9199). https://doi.org/10.1016/S0140-6736(99)03842-8

Failure of elimination of paternal mitochondrial DNA in abnormal embryos. / St John, Justin; Sakkas, Denny; Dimitriadi, Konstantina; Barnes, Annette; Maclin, Victoria; Ramey, Jacques; Barratt, Christopher; De Jonge, Christopher.

In: Lancet, Vol. 355, No. 9199, 15.01.2000.

Research output: Contribution to journalArticle

St John, J, Sakkas, D, Dimitriadi, K, Barnes, A, Maclin, V, Ramey, J, Barratt, C & De Jonge, C 2000, 'Failure of elimination of paternal mitochondrial DNA in abnormal embryos', Lancet, vol. 355, no. 9199. https://doi.org/10.1016/S0140-6736(99)03842-8
St John, Justin ; Sakkas, Denny ; Dimitriadi, Konstantina ; Barnes, Annette ; Maclin, Victoria ; Ramey, Jacques ; Barratt, Christopher ; De Jonge, Christopher. / Failure of elimination of paternal mitochondrial DNA in abnormal embryos. In: Lancet. 2000 ; Vol. 355, No. 9199.
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