Factors associated with receipt of hematopoietic cell transplantation for acute lymphoblastic leukemia

Jayadev Manikkam Umakanthan, Baojiang Chen, Krishna Gundabolu, Vijaya R. Bhatt

Research output: Contribution to journalArticle

Abstract

Aim: To evaluate practice patterns of hematopoietic cell transplantation (HCT) for acute lymphoblastic leukemia. Materials & methods: We utilized the National Cancer Database to extract patient-level data of adults (aged 18-80 years) diagnosed with acute lymbhoblastic leukemia between 2003 and 2012. We performed multivariable logistic regression to determine variables associated with the use of HCT. Results: Out of a total of 11,871 patients, 12.7% received HCT. In a multivariate analysis, older age, male sex, higher Charlson co-morbidity score, nonacademic treatment center, poor education and Medicare/Medicaid or no insurance were associated with lower likelihood of receiving HCT. Conclusion: Our study demonstrates variations in the utilization of HCT based on socioeconomic and health system factors.

Original languageEnglish (US)
Pages (from-to)1253-1260
Number of pages8
JournalFuture Oncology
Volume14
Issue number13
DOIs
StatePublished - Jun 2018

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Keywords

  • acute lymphoblastic leukemia
  • healthcare disparities
  • hematopoietic cell transplant
  • transplant utilization

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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