Evidence of point-source exposure to Neospora caninum and protective immunity in a herd of beef cows

Milton M. McAllister, Camilla Björkman, Richard Anderson-Sprecher, Douglas G Rogers

Research output: Contribution to journalArticle

126 Citations (Scopus)

Abstract

Objective - To determine whether cows with evidence of previous infection with Neospora caninum were less likely to abort or give birth prematurely during an outbreak of neosporosis, compared with herdmates with evidence of primary infection. Design - Cohort study. Animals - 208 pregnant beef cows. Procedures - Aborted fetuses and calves born prematurely were examined during an outbreak of neosporosis in a herd of beef cows. Sera were collected from all cows during the outbreak and again 71 days later. Cows were classified into groups on the basis of normal and abnormal reproductive outcomes. Sera were examined, using an avidity ELISA procedure for N caninum, and results were compared between groups and among time points. Results - Antibody concentrations decreased significantly and IgG avidity values increased significantly over time. During the outbreak, cows with normal reproductive outcomes were significantly more likely to have high IgG avidity values than cows with abnormal reproductive outcomes. Conclusions and Clinical Relevance - The herd had numerous abortions and premature births with evidence of recent point-source exposure to N caninum. Therefore, to reduce risk of transmission of N caninum to cattle, attempts should be made to prevent canine feces from contaminating feed, especially feedstuffs used to prepare mixed rations for cattle. Cows with evidence of previous exposure to N caninum were less likely to abort or give birth prematurely during the outbreak than cows with primary infections with N caninum; this finding suggests development of protective immunity in previously infected cows.

Original languageEnglish (US)
Pages (from-to)881-887
Number of pages7
JournalJournal of the American Veterinary Medical Association
Volume217
Issue number6
DOIs
StatePublished - Sep 15 2000

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Neospora
Neospora caninum
beef cows
Disease Outbreaks
Immunity
immunity
herds
cows
neosporosis
Immunoglobulin G
Infection
Parturition
Aborted Fetus
Premature Birth
Serum
Feces
infection
Canidae
premature birth
Cohort Studies

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Evidence of point-source exposure to Neospora caninum and protective immunity in a herd of beef cows. / McAllister, Milton M.; Björkman, Camilla; Anderson-Sprecher, Richard; Rogers, Douglas G.

In: Journal of the American Veterinary Medical Association, Vol. 217, No. 6, 15.09.2000, p. 881-887.

Research output: Contribution to journalArticle

McAllister, Milton M. ; Björkman, Camilla ; Anderson-Sprecher, Richard ; Rogers, Douglas G. / Evidence of point-source exposure to Neospora caninum and protective immunity in a herd of beef cows. In: Journal of the American Veterinary Medical Association. 2000 ; Vol. 217, No. 6. pp. 881-887.
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