Evaluation of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry to differentiate between Candida albicans and Candida dubliniensis

Amity L. Roberts, Aqilah Alelew, Peter Charles Iwen

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF-MS) analysis in conjunction with the direct formic acid (FA) sample processing method was evaluated for the ability to differentiate the closely related species of Candida albicans and Candida dubliniensis. The results showed that MALDI-TOF-MS, using the direct FA method, was reliable to differentiate between these species.

Original languageEnglish (US)
Pages (from-to)73-76
Number of pages4
JournalDiagnostic Microbiology and Infectious Disease
Volume85
Issue number1
DOIs
StatePublished - May 1 2016

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formic acid
Candida albicans
Candida
Mass Spectrometry
Lasers

Keywords

  • Candida dubliniensis
  • ITS1
  • ITS4
  • MALDI-TOF-MS

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

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abstract = "Matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF-MS) analysis in conjunction with the direct formic acid (FA) sample processing method was evaluated for the ability to differentiate the closely related species of Candida albicans and Candida dubliniensis. The results showed that MALDI-TOF-MS, using the direct FA method, was reliable to differentiate between these species.",
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AU - Iwen, Peter Charles

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AB - Matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF-MS) analysis in conjunction with the direct formic acid (FA) sample processing method was evaluated for the ability to differentiate the closely related species of Candida albicans and Candida dubliniensis. The results showed that MALDI-TOF-MS, using the direct FA method, was reliable to differentiate between these species.

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KW - ITS1

KW - ITS4

KW - MALDI-TOF-MS

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